Spinal Segmental Contributions to Sitting & Reaching in Cerebral Palsy
脊柱节段对坐姿的影响
基本信息
- 批准号:8231295
- 负责人:
- 金额:$ 29.45万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2011
- 资助国家:美国
- 起止时间:2011-03-01 至 2015-01-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAdultAgeBehavioralBirthCerebral PalsyChestChildChronic DiseaseClassificationClinicalCross-Sectional StudiesDataDevelopmentEquilibriumFoundationsFunctional disorderGoalsHeadInfantKnowledgeLearningLongitudinal StudiesLumbar RegionsMeasuresMethodsModelingMotorMovementMuscleMusculoskeletal EquilibriumOutcomePatternPelvisPopulationProcessRehabilitation therapyResearchSeveritiesSpinalStagingSystemTimeTrainingVertebral columnbaseclinical practicedisabilitygraspimprovedkinematicsmotor deficitnovelnovel strategiesoutcome forecastpreventpublic health relevanceresearch studyresponseskills
项目摘要
DESCRIPTION (provided by applicant): The long-term goal of this research is 1) to understand mechanisms used by typically developing (TD) infants in attaining head & trunk control for the development of sitting balance and associated reaching skills, and 2) to apply that knowledge to understanding and improving these skills in children with cerebral palsy (CP). While trunk postural control creates the basis for reaching skills, little is known about how spinal stability develops; in fact there are almost no clinical measures of intermediate stages of trunk stability. In the case of children with CP this lack of knowledge is critical. Our experiments address these limitations. Experiments will determine developmental changes in kinematics of head stability, trunk muscle activation patterns and patterns of reaching movements with different levels of trunk support in TD infants and children with CP. Specific Aim 1 is a longitudinal study evaluating contributions of spinal segments to head stability and reaching skills in 3-9 month old TD infants as they gain sitting balance. We hypothesize: 1) head stability emerges first at higher levels of trunk support and stability progresses sequentially down the spine in a time dependent manner, associated with the rostro-caudal development of coordinated muscle response patterns during sitting; and 2) emergence of efficient reaching movements is associated with the mastery of postural control at a given level of trunk development. Specific Aim 2 is a cross-sectional study evaluating contributions of spinal segments to trunk stability and reaching in children with moderate to severe CP. We hypothesize that 1) within children with various levels of severity of CP (Gross Motor Function Classification System levels III, IV, V) we will see arrested levels of spinal development along a continuum of that which is seen during sitting balance development in TD children; thus lack of sitting spinal control reflects deficits in coordination at a specific spinal level; 2) reaching deficits will be associated with postural control deficits at specific spinal levels. The study of segmental contributions to spinal control is novel and challenges current clinical concepts for assessment and treatment of sitting development; thus it brings critical new information to our understanding of both typical development and constrained development in children with CP.
PUBLIC HEALTH RELEVANCE: Knowledge about progression of trunk control in TD infants and children with CP will provide important information for clinicians trying to help children with CP gain independent sitting and manipulation skills. This novel approach will be the basis for the development of new methods to assess and treat postural and reaching dysfunction. Unlike most previous research, this paradigm addresses the needs of those children with the most severe motor disabilities.
描述(由申请人提供):本研究的长期目标是 1) 了解典型发育 (TD) 婴儿在获得头部和躯干控制以发展坐姿平衡和相关伸手技能时所使用的机制,以及 2)运用这些知识来理解和提高脑瘫 (CP) 儿童的这些技能。虽然躯干姿势控制为达到技能奠定了基础,但人们对脊柱稳定性如何发展知之甚少。事实上,几乎没有躯干稳定性中期阶段的临床测量方法。对于患有脑瘫的儿童来说,缺乏知识是至关重要的。我们的实验解决了这些限制。实验将确定 TD 婴儿和 CP 儿童的头部稳定性运动学、躯干肌肉激活模式以及不同躯干支撑水平下的伸手运动模式的发育变化。具体目标 1 是一项纵向研究,评估脊柱节段对 3-9 个月大 TD 婴儿获得坐姿平衡时的头部稳定性和伸展技能的贡献。我们假设:1)头部稳定性首先出现在较高水平的躯干支撑下,并且稳定性以时间依赖的方式沿着脊柱顺序进展,与坐姿期间协调肌肉反应模式的头尾发育相关; 2)有效的伸展运动的出现与在躯干发育的特定水平上对姿势控制的掌握有关。具体目标 2 是一项横断面研究,评估脊柱节段对中度至重度脑瘫儿童躯干稳定性和伸展能力的贡献。我们假设 1) 在患有不同严重程度 CP(粗大运动功能分类系统 III、IV、V 级)的儿童中,我们将看到脊柱发育水平停滞,与 TD 儿童坐位平衡发育过程中所见的水平一致;因此,坐姿脊柱控制的缺乏反映了特定脊柱水平的协调缺陷; 2) 到达缺陷与特定脊柱水平的姿势控制缺陷相关。节段对脊柱控制的贡献的研究是新颖的,挑战了当前评估和治疗坐位发展的临床概念;因此,它为我们理解脑瘫儿童的典型发育和受限发育提供了重要的新信息。
公众健康相关性:关于 TD 婴儿和 CP 儿童躯干控制进展的知识将为试图帮助 CP 儿童获得独立坐姿和操作技能的临床医生提供重要信息。这种新方法将成为开发评估和治疗姿势和伸展功能障碍的新方法的基础。与之前的大多数研究不同,这种范例解决了那些患有最严重运动障碍的儿童的需求。
项目成果
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MARJORIE HINES WOOLLACOTT其他文献
MARJORIE HINES WOOLLACOTT的其他文献
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{{ truncateString('MARJORIE HINES WOOLLACOTT', 18)}}的其他基金
Spinal Segmental Contributions to Sitting & Reaching in Cerebral Palsy
脊柱节段对坐姿的影响
- 批准号:
8468188 - 财政年份:2011
- 资助金额:
$ 29.45万 - 项目类别:
Spinal Segmental Contributions to Sitting & Reaching in Cerebral Palsy
脊柱节段对坐姿的影响
- 批准号:
8042759 - 财政年份:2011
- 资助金额:
$ 29.45万 - 项目类别:
Spinal Segmental Contributions to Sitting & Reaching in Cerebral Palsy
脊柱节段对坐姿的影响
- 批准号:
8608569 - 财政年份:2011
- 资助金额:
$ 29.45万 - 项目类别:
DYNAMIC BALANCE CONTROL IN CHILDREN WITH CEREBRAL PALSY
脑瘫儿童的动态平衡控制
- 批准号:
2848631 - 财政年份:1999
- 资助金额:
$ 29.45万 - 项目类别:
DYNAMIC BALANCE CONTROL IN CHILDREN WITH CEREBRAL PALSY
脑瘫儿童的动态平衡控制
- 批准号:
6187795 - 财政年份:1999
- 资助金额:
$ 29.45万 - 项目类别:
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