LENTIVIRAL VECTORS AS A RESEARCH RESOURCE AT THE ONPRC

慢病毒载体作为 ONPRC 的研究资源

• 批准号: 7561949
• 负责人: Gregory A Dissen
• 金额: $ 1.47万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7561949
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Development; Disease; Funding; Goals; Grant; Health; Human; Institution; Lentivirus Vector; Production; Research; Research Personnel; Resources; Scientist; Services; Source; System; Thinking; United States National Institutes of Health; gene therapy; nonhuman primate; tool; virology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The aim of this project was to develop a lentiviral vector-delivery system for use at the ONPRC. This goal is being carried on by the establishment of the Lentiviral Production Service within the Virology Core which will continue aiding center scientists in the use of specific lentiviral constructs. The lentiviral vector is one of the gene therapy systems thought to have potential use in humans. Thus development of the lentiviral system as a tool, especially in nonhuman primates will have translational value to human health and the treatment of disease.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 该项目的目的是开发一种供 ONPRC 使用的慢病毒载体传递系统。 这一目标正在通过在病毒学核心内建立慢病毒生产服务来实现，该服务将继续帮助中心科学家使用特定的慢病毒构建体。 慢病毒载体是被认为在人类中具有潜在用途的基因治疗系统之一。 因此，慢病毒系统作为一种工具的开发，特别是在非人类灵长类动物中，将对人类健康和疾病治疗具有转化价值。