Mind-Body Exercise in the Management of Cardiac Disease

身心锻炼在心脏病治疗中的应用

基本信息

批准号：
7356027
负责人：
GLORIA Y YEH
金额：
$ 13万
依托单位：
HARVARD MEDICAL SCHOOL
依托单位国家：
美国
项目类别：
财政年份：
2005
资助国家：
美国
起止时间：
2005-02-01 至 2010-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7356027
关键词：
Accident and Emergency department Acupuncture procedure Adherence Adult Adverse event Affect Age Anxiety Attitude Autonomic nervous system Belief Cardiac Cardiomyopathies Cardiovascular Diseases Caring Categories Chronic Class Client satisfaction Clinical Clinical Trials Design Consultations Coronary Arteriosclerosis Data Databases Development Diastolic heart failure Disease Dose Evaluation Exercise Exercise Tolerance Feasibility Studies Future General Population Goals Guidelines Health Health Services Research Heart Diseases Heart failure Herb Heterogeneity Hospitalization Hypertension Individual Intervention Lead Left Ventricular Dysfunction Life Malignant Neoplasms Massachusetts Medical Medicare Meditation Mental Depression Mentors Mind Mind-Body Intervention Minority Modality Moods Morbidity - disease rate Movement Myocardial Neurohormones Outcome Outpatients Patient Preferences Patients Pattern Pharmaceutical Preparations Physical activity Physiological Physiology Population Prayers Preparation Prevalence Procedures Public Health Publishing Qi Gong Quality of life Randomized Randomized Clinical Trials Randomized Controlled Trials Rate Recruitment Activity Rehabilitation Centers Rehabilitation therapy Relaxation Relaxation Techniques Reporting Research Research Personnel Role Safety Sampling Self Care Self Efficacy Societies Standards of Weights and Measures Structure Surveys Syndrome Tai Ji Testing Time Treatment/Psychosocial Effects Visit Week Yoga base body-mind career chiropracty compliance behavior cost cost effectiveness design expectation improved older patient patient oriented research preference prescription document prescription procedure programs psychosocial response skills stress management trend

项目摘要

DESCRIPTION (provided by applicant): Dr. Gloria Yeh's long-term career goal is to become an independent clinician investigator focusing on the critical evaluation, mechanistic understanding, and successful integration of evidence-based complementary and alternative medical (CAM) therapies for patients with cardiovascular disease and heart failure. Her immediate career objectives are: to enhance her methodological skills in clinical trial design and health services research through coursework, educational seminars, and the development of three rigorous, mentored studies; to understand the potential psychosocial and physiological mechanisms by which mind-body exercise can improve clinical outcome in cardiac patients; and to define the potential role of mind-body exercise and other CAM modalities in the current management of patients with cardiovascular disease. This proposal includes three projects with a particular focus on mind-body exercise in patients with chronic heart failure. The first will be a secondary database analysis describing the patterns and prevalence of CAM use in a large national sample of patients with cardiac disease and examining the factors associated with perceived beneficial use of tai chi, qigong, or yoga. The second and main project will be a pilot randomized controlled trial (n=20) evaluating study feasibility and safety of a 12-week tai chi/qigong program in older patients with diastolic heart failure. This study will provide important preliminary data regarding potential psychosocial effects (e.g., change in self-efficacy, mood, quality-of-life) and physiological mechanisms (e.g., change in exercise capacity, autonomic tone, neurohormone status) in preparation for a future R01application for a larger randomized clinical trial. The third project will assess current cardiac rehabilitation programs available to patients with cardiovascular disease and heart failure to begin to explore the incorporation of mind-body exercise into these rehabilitation programs and to understand the perceived successful psychosocial program components (e.g., factors that can enhance patient self-efficacy and program adherence). Completion of the proposed research and career development activities will enhance Dr. Yeh's ability to conduct patient-oriented research and allow her to achieve her career goal of becoming an independent clinical researcher investigating CAM therapies and its applications to patients with cardiac disease.

描述（由申请人提供）：Gloria Yeh 博士的长期职业目标是成为一名独立的临床研究者，专注于对患有以下疾病的患者进行批判性评估、机制理解以及基于证据的补充和替代医学 (CAM) 疗法的成功整合心血管疾病和心力衰竭。她的近期职业目标是：通过课程作业、教育研讨会和开展三项严格的指导性研究，提高她在临床试验设计和卫生服务研究方面的方法技能；了解身心锻炼可以改善心脏病患者临床结果的潜在心理社会和生理机制；并确定身心锻炼和其他 CAM 模式在当前心血管疾病患者管理中的潜在作用。该提案包括三个项目，特别关注慢性心力衰竭患者的身心锻炼。第一个是二次数据库分析，描述全国范围内心脏病患者的大型样本中 CAM 使用的模式和流行率，并检查与太极、气功或瑜伽的有益使用相关的因素。第二个也是主要项目将是一项随机对照试验（n=20），评估针对患有舒张性心力衰竭的老年患者进行为期 12 周的太极拳/气功项目的可行性和安全性。这项研究将提供有关潜在社会心理影响（例如，自我效能、情绪、生活质量的变化）和生理机制（例如，运动能力、自主神经张力、神经激素状态的变化）的重要初步数据，为未来做好准备R01申请更大规模的随机临床试验。第三个项目将评估当前可供心血管疾病和心力衰竭患者使用的心脏康复计划，以开始探索将身心锻炼纳入这些康复计划，并了解被认为成功的心理社会计划组成部分（例如，可以增强患者能力的因素）。自我效能和计划遵守）。完成拟议的研究和职业发展活动将增强 Yeh 博士进行以患者为导向的研究的能力，并使她能够实现成为一名独立的临床研究员，研究 CAM 疗法及其在心脏病患者中的应用。