CLINICAL FASTEEM INSTRUMENT

临床 FASTEEM 仪器

• 批准号: 8170406
• 负责人: ZOYA VOLYNSKAYA
• 金额: $ 1.9万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8170406
• 关键词: Atherosclerosis; Cervical dysplasia; Clinical; Computer Retrieval of Information on Scientific Projects Database; Diagnosis; Diagnostic Procedure; Diffuse; Fluorescence; Fluorescence Spectroscopy; Fostering; Funding; Grant; Institution; Light; Optics; Research; Research Personnel; Resources; Sampling; Source; Spectrum Analysis; Tissues; Translational Research; United States National Institutes of Health; instrument; malignant breast neoplasm; malignant mouth neoplasm; optical fiber

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have investigated the usage of the combination of diffuse reflectance and intrinsic fluorescence spectroscopy to diagnose cervical dysplasia, oral cancer, atherosclerosis, and breast cancer. We are developing a mini-DRS/IFS clinical instrument that will be available for users outside of the LBRC. The purposes of this project are to foster clinical translational research in optical spectroscopy; and to familiarize young/new investigators with the methods of diagnostic spectroscopy. The LBRC will provide DRS/IFS spectroscopy instrument capable of collecting diffuse white light spectral reflectance and 340nm-excited fluorescence light. The spectra are acquired in ~1 sec by means of a DRS/IFS optical fiber probe, which samples 1mm2 regions of tissue.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此，可以在其他清晰的条目中表示。列出的机构是 对于中心，这不一定是调查员的机构。 我们已经研究了弥漫性反射率和内在荧光光谱的组合，以诊断宫颈发育不良，口腔癌，动脉粥样硬化和乳腺癌。我们正在开发一个Mini-DRS/IFS临床仪器，可用于 LBRC之外的用户。该项目的目的是促进光谱学的临床翻译研究。并熟悉年轻/新研究人员的诊断光谱方法。 LBRC将提供DRS/IFS光谱仪器，能够收集弥散的白光光谱反射率和340nm激发的荧光。光谱是通过DRS/IFS光纤探针在〜1秒内获取的，该光纤探针采样了1mm2的组织区域。