Clinical Core

临床核心

• 批准号: 7930106
• 负责人: John A Bartlett
• 金额: $ 27.38万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-15 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7930106
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Area; Automobile Driving; Back; Clinical; Clinical Investigator; Clinical Research; Collaborations; Communities; Databases; Development; Environment; Faculty; Funding; Good Clinical Practice; HIV; Human Subject Research; Institutes; Interdisciplinary Study; International; Laboratories; Laboratory Scientists; Link; Malignant Neoplasms; Mission; Pathogenesis; Patients; Recruitment Activity; Research; Research Personnel; Services; Site; Specimen; Translating; Universities; bench to bedside; global health; investigator-initiated translational research; novel; patient oriented research; repository; symposium

Core F The Duke University CFAR Clinical Core (Core F) provides a dynamic, higlily motivated and effective environment for HIV-related clinical studies within the Duke CFAR. In line with the overall mission for a CFAR, this Core provides "value-added" to facilitate patient-oriented research by providing clinical research expertise, regulatory support, access to patient specimens, and community involvement. The Core is responsive to the needs of the investigators within Duke and has aggressively pursued opportunities to expand clinical opportunities in Durham and through international sites. This Core has three specific aims: 1) To facilitate cutting edge patient-oriented research by clinical and laboratory investigators through the development of new Core services responsive to investigator needs and CFAR priorities such as international collaborations, and an enhanced database linked to a specimen repository; 2) To catalyze patient-oriented research collaborations between Duke CFAR investigators, especially within CFAR priority areas of HIV pathogenesis and AIDS-associated malignancies, by translating the hypotheses of Duke CFAR investigators into clinical studies, bringing novel clinical observations back to laboratory investigators, facilitating and leading interdisciplinary research teams, and actively participating in CFAR conferences and symposia; 3) To attract new investigators into patient-oriented research investigating HIV/AIDS by emphasizing interdisciplinary research efforts, communicating with key partners such as the Duke Global Health Institute and the Duke Comprehensive Cancer Institute, suggesting new collaborations, and recruiting new Duke faculty. Clinical Core accomplishments from the first four years suggest that the Clinical Core will thrive as the centerpiece of patient-oriented research within the CFAR in the next funding cycle, driving the CFAR to realize its scientific priorities.

核心f 杜克大学CFAR临床核心（核心F）为杜克CFAR内的HIV相关临床研究提供了动态，灵活的动机和有效的环境。与CFAR的整体任务一致，该核心通过提供临床研究专业知识，监管支持，访问患者标本和社区参与，提供“增值”，以促进以患者为导向的研究。核心对杜克州内调查人员的需求有所反应，并积极追求机会 扩大达勒姆和国际地点的临床机会。该核心具有三个具体的目的：1）促进临床和实验室研究人员以患者为导向的尖端研究，通过开发响应研究者需求和CFAR优先级的新核心服务，例如国际合作，以及与标本储存库相关的增强数据库； 2）通过将Duke CFAR研究者的假设转化为临床研究的假设，将新颖的临床观察结果转化为实验室研究员，促进和领导的互助研究团队，并在CFAR的优先领域催化杜克CFAR研究者之间的患者研究合作，尤其是在CFAR优先级和与AIDS相关的恶性肿瘤之间的促进患者的研究合作。座谈会； 3）通过强调跨学科研究工作来吸引新的研究人员研究艾滋病毒/艾滋病的研究，与杜克大学全球卫生研究所和杜克大学综合癌症研究所等关键伙伴进行沟通，建议进行新的合作，并招募新的杜克大学。最初四年以来的临床核心成就表明，临床核心将在下一个融资周期中作为CFAR中以患者为导向的研究的核心，推动CFAR实现其科学优先事项。