CENTER FOR VISUAL AND COGNITIVE NEUROSCIENCE

视觉和认知神经科学中心

基本信息

批准号：
8168448
负责人：
MARK E. McCourt
金额：
$ 212.63万
依托单位：
NORTH DAKOTA STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-08-25 至 2011-08-24
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8168448
关键词：
Advisory Committees Agnosia Amblyopia Arts Attention Attention deficit hyperactivity disorder Autistic Disorder Behavior Centers of Research Excellence Cognition Cognitive Commit Computer Retrieval of Information on Scientific Projects Database Computers Dementia Disease Dyslexia Electroencephalography Emotions Faculty Funding Future Grant Impaired cognition Institution Knowledge Laboratories Laboratory Technicians Maintenance Measures Mental Depression Mentors Monoclonal Antibody R24 Multiple Sclerosis Nervous System Physiology Parkinson Disease Perceptual Disorders Pilot Projects Post-Traumatic Stress Disorders Postdoctoral Fellow Prevalence Recruitment Activity Research Research Infrastructure Research Personnel Research Project Grants Resources Schizophrenia Sensory Source Structure Syndrome Talents Time Training United States National Institutes of Health Visual Visual Perception Visual attention age related cognitive neuroscience density executive function graduate student infrastructure development laboratory facility member neuroimaging neuromechanism normal aging public health relevance success translational neuroscience visual cognition

项目摘要

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): We propose renewal of our COBRE at NDSU. Our research focus is Visual and Cognitive Neuroscience. We describe four thematically interrelated primary projects directed by promising junior and senior investigators, which examine the neural mechanisms and functional significance of visual perception, visual attention, visual cognition and action. Our Specific Aims are: SPECIFIC AIM #1: To develop successful, independent, self-sustaining research projects for COBRE Project Directors to enable future success in obtaining R01 funding. This aim will be accomplished by obtaining COBRE support for thematically articulated research projects and by establishing an Administrative Core consisting of the PI/PD, a two-member Internal Advisory Committee, a three-member External Advisory Committee, as well as a group of five Project Mentors. SPECIFIC AIM #2: To enhance research infrastructure at NDSU through maintenance of multiuser Core laboratory facilities. The projects of the COBRE utilize state-of-the-art EEG neuroimaging to measure relationships between the structure and function of the nervous system and the behavior it governs. We will continue to enhance research infrastructure by supporting the Core laboratory for High-Density EEG, staffed by a full-time EEG laboratory technician and two full-time computer programmers. SPECIFIC AIM #3: To expand NDSU's research capability in visual and cognitive neuroscience by recruiting an additional faculty member with research expertise in translational neuroscience. We propose to recruit a visual or cognitive neuroscientist during the first year of the COBRE project. This new recruit will augment our critical mass of research talent that will sustain the Center beyond the initial years of COBRE support. This newly recruited faculty member will be eligible for CVCN support through a Pilot Project mechanism. SPECIFIC AIM #4: To establish a nationally recognized Center for Visual and Cognitive Neuroscience at NDSU. The realization of Specific Aims 1-3 will create a center of research excellence at NDSU which is guaranteed to attract additional quality faculty, postdoctoral fellows and graduate students committed to cutting-edge research in visual and cognitive neuroscience. The NDSU Center for Visual and Cognitive Neuroscience will be competitive for Institutional Training Grants (T32), Research Project Grants (ROI), and Infrastructure Development Grants (R24) which will sustain the Center beyond the initial years of support. PUBLIC HEALTH RELEVANCE (provided by applicant): Disordered perception, cognition, emotion, attention and executive function are hallmarks of debilitating and costly disease syndromes (ADHD, ARMD, agnosia, amblyopia, autism, depression, dementia, dyslexia, hemineglect, multiple sclerosis, Parkinson's disease, PTSD, and schizophrenia). Equally significant is the prevalence of such disorders in normal age-related sensory and cognitive decline. This COBRE is dedicated to the discovery of knowledge that illuminates and potentially ameliorates these conditions.

该子项目是利用该技术的众多研究子项目之一资源由 NIH/NCRR 资助的中心拨款提供。子项目及研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金，因此可以在其他 CRISP 条目中表示。列出的机构是对于中心来说，它不一定是研究者的机构。描述（由申请人提供）：我们建议在 NDSU 更新我们的 COBRE。我们的研究重点是视觉和认知神经科学。我们描述了由有前途的初级和高级研究人员指导的四个主题相关的主要项目，这些项目检查视觉感知、视觉注意力、视觉认知和行动的神经机制和功能意义。我们的具体目标是：具体目标#1：为 COBRE 项目总监开发成功、独立、自我维持的研究项目，以便未来成功获得 R01 资金。这一目标将通过获得 COBRE 对主题明确的研究项目的支持以及建立一个由 PI/PD、一个由两名成员组成的内部咨询委员会、一个由三名成员组成的外部咨询委员会以及一个由 5 名成员组成的小组组成的行政核心来实现。项目导师。具体目标#2：通过维护多用户核心实验室设施来加强 NDSU 的研究基础设施。 COBRE 的项目利用最先进的脑电图神经影像来测量神经系统的结构和功能及其控制的行为之间的关系。我们将继续加强研究基础设施，支持高密度脑电图核心实验室，该实验室配备一名全职脑电图实验室技术人员和两名全职计算机程序员。具体目标#3：通过招募一名具有转化神经科学研究专业知识的额外教员来扩大 NDSU 在视觉和认知神经科学方面的研究能力。我们建议在 COBRE 项目的第一年招募一名视觉或认知神经科学家。这位新招募的人员将增加我们关键的研究人才数量，从而使该中心在 COBRE 支持的最初几年之后继续维持下去。这位新招募的教员将有资格通过试点项目机制获得 CVCN 支持。具体目标#4：在 NDSU 建立国家认可的视觉和认知神经科学中心。具体目标 1-3 的实现将在 NDSU 创建一个卓越研究中心，保证吸引更多致力于视觉和认知神经科学前沿研究的优质教师、博士后研究员和研究生。 NDSU 视觉和认知神经科学中心将在机构培训补助金 (T32)、研究项目补助金 (ROI) 和基础设施发展补助金 (R24) 方面具有竞争力，这些补助金将在最初几年的支持之后继续维持该中心。公共卫生相关性（由申请人提供）：知觉、认知、情绪、注意力和执行功能紊乱是使人衰弱且代价高昂的疾病综合征的标志（多动症、ARMD、失认症、弱视、自闭症、抑郁症、痴呆、阅读障碍、偏瘫、多发性硬化症、帕金森病、创伤后应激障碍和精神分裂症）。同样重要的是，此类疾病在与年龄相关的正常感觉和认知衰退中普遍存在。该 COBRE 致力于发现能够阐明并有可能改善这些状况的知识。