High Resolution Neuro-MRI

高分辨率神经磁共振成像

• 批准号: 8253453
• 负责人: Shahin Pourrahimi
• 金额: $ 20.42万
• 依托单位: SUPERCONDUCTING SYSTEMS, INC
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-15 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8253453
• 关键词: Architecture; Area; Brain; Businesses; Care Technology Points; Clinical; Craniocerebral Trauma; Custom; Development; Devices; Diagnostic; Electricity; Electronics; Elements; Funding; General Hospitals; Goals; Head; Helium; Human; Human Resources; Image; Industrialization; Liquid substance; Location; MRI Scans; Magnetic Resonance Imaging; Magnetism; Massachusetts; Modeling; National Institute of Biomedical Imaging and Bioengineering; Neurologic; Neurological emergencies; Patients; Performance; Phase; Positioning Attribute; RF coil; Research; Resolution; Rural; Scanning; Stroke; System; Technology; United States National Institutes of Health; Vertebral column; Work; base; cold temperature; commercialization; cost; cryostat; design; experience; improved; meetings; next generation; novel; operation; point of care; pre-clinical; programs; research and development; success; technology development; web site; whole body imaging

DESCRIPTION (provided by applicant): This program will develop and manufacture a realistic Point-of-Care Neurological MRIScanner with a novel architecture specifically designed for imaging a human brain and C-spine based on a modern low cost magnet, which features ease of operation and low operating cost. Once the functionality of the scanner is demonstrated, the scanner can be used to image other parts of the head in addition to the brain. Also, the scanner that we propose has a through bore and allows whole-body scanning on a large fraction of the human public and offers MRI scans to the public in the rural locations as well as under-served areas. The scanner we intend to develop will work wherever there can be electricity. PUBLIC HEALTH RELEVANCE: According to NIH/NIBIB website, "There is a critical need for developing improved and rapid diagnostic information for patients experiencing neurological emergencies such as stroke and head injury." NIBIB lists low-cost imaging as one of the four areas that are in need of Point-of-Care technology development. This program will develop and manufacture a realistic Point-of-Care Neurological MRI Scanner with a novel architecture specifically designed for imaging a human brain and C-spine based on a modern low cost magnet, which features ease of operation and low operating cost. The reasons we refer to this B0 magnet as realistic are: i) In the Phase I work we demonstrated all the key elements of such a magnet, ii) the entire B0 magnet with its cryocooler and compressor weighs less than 500 kg, and iii) development of the proposed cryogen-free MRI magnet is based on proven and reliable low temperature superconductors, and not on superconductors that have been under development. Our technology is here now.

描述（由申请人提供）：该程序将开发和制造现实的护理神经系统MRISCANNER，其新颖的建筑专门设计用于基于现代低成本磁铁的人类大脑和C型的成像，该磁铁的操作易于操作和低工作成本。一旦证明了扫描仪的功能，扫描仪可用于除大脑外的其他部位。此外，我们建议的扫描仪具有钻孔，并允许对大部分人类公众进行全身扫描，并在农村地区和服务不足的地区向公众提供MRI扫描。我们打算开发的扫描仪将在可能有电力的任何地方起作用。 公共卫生相关性：根据NIH/NIBIB网站的说法，“对于患有中风和头部损伤等神经系统紧急情况的患者，需要开发改进和快速的诊断信息。”尼比布将低成本成像列为需要护理点技术开发的四个领域之一。该程序将开发和制造现实的护理神经系统MRI扫描仪，其新型建筑专门设计用于基于现代低成本磁铁的人类大脑和C型螺旋，该磁铁的操作易于操作和低工作成本。我们将此B0磁体称为现实的原因是：i）在I阶段的工作中，我们证明了这种磁铁的所有关键要素，ii）整个B0磁铁及其冷冻机和压缩机的重量小于500 kg，iiii）的发展基于可靠的低温和低温超级尺寸，并不是在拟议中的无冻磁力的发展。我们的技术现在在这里。