BIOMEDICAL PROTEOMICS FACILITY

生物医学蛋白质组学设施

• 批准号: 8357101
• 负责人: NAWAL BOUKLI
• 金额: $ 6.5万
• 依托单位: UNIVERSIDAD CENTRAL DEL CARIBE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357101
• 关键词: Academia; Address; Basic Science; Biomedical Research; Clinical Research; Collaborations; Communities; Data; Drug Industry; Funding; Gel; Goals; Grant; Industry; Island; Mass Spectrum Analysis; Methods; National Center for Research Resources; Play; Principal Investigator; Protein Analysis; Proteins; Proteomics; Puerto Rico; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Proposals; Resources; Role; Scientist; Services; Source; Techniques; Technology; Training and Education; Translational Research; United States National Institutes of Health; Universities; base; cost; interest

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. A need for a proteomic facility service at UCC has been identified by the local and external research community to support basic and translational and clinical research efforts. Currently, this service is provided on a limited basis due to the lack of funding and technical support. The Biomedical Proteomics Facility (BPF) at the UCC will provide researchers with the ability to analyze and identify proteins to address basic and translational research questions that could not be previously studied due to the lack of support in proteomics techniques. The scientific support provided by BPF will facilitate the integration of proteomics into basic and translational research projects and submission of new research proposals to granting agencies. The following SPECIFIC AIMS will be carried out: Specific Aim #1: Provide scientific and technical support to principal investigators within UCC and other universities in Puerto Rico for the accomplishment of research projects. Specific Aim #2: Attract new scientist to the technique of proteomics and interest them in establishing collaborations exploiting the technologies available at BPF. Specific Aim #3: Establish collaboration with scientists in the academia and industry of Puerto Rico. Specific Aim #4: Provide education and training in proteomic methods. The goal of this facility is the application of sensitive and quantitative technologies to relevant biomedical and basic scientific questions. So far the BPF has played an essential role in supplying 2D gels and mass spectrometry preliminary data for several researchers. Ultimately, the BPF will facilitate the establishment of partnerships between the academia and pharmaceutical industry, situating UCC at the vanguard in protein analysis and contributing to the recruitment of new scientist and the establishment of collaborations in and outside of the island.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 当地和外部研究界已确定 UCC 需要蛋白质组学设施服务，以支持基础研究、转化研究和临床研究工作。目前，由于缺乏资金和技术支持，这项服务的提供有限。 UCC 的生物医学蛋白质组学设施 (BPF) 将为研究人员提供分析和鉴定蛋白质的能力，以解决以前由于缺乏蛋白质组学技术支持而无法研究的基础和转化研究问题。 BPF 提供的科学支持将促进将蛋白质组学纳入基础和转化研究项目，并向资助机构提交新的研究提案。 将实现以下具体目标： 具体目标#1：为 UCC 和波多黎各其他大学的主要研究人员提供科学和技术支持，以完成研究项目。 具体目标#2：吸引新科学家研究蛋白质组学技术，并使他们有兴趣建立利用 BPF 现有技术的合作。 具体目标#3：与波多黎各学术界和工业界的科学家建立合作。 具体目标#4：提供蛋白质组学方法的教育和培训。 该设施的目标是将敏感和定量技术应用于相关的生物医学和基础科学问题。 到目前为止，BPF 在为几位研究人员提供 2D 凝胶和质谱初步数据方面发挥了重要作用。最终，BPF 将促进学术界和制药行业之间建立合作伙伴关系，使 UCC 处于蛋白质分析领域的先锋地位，并有助于招募新科学家以及在岛内外建立合作。