Acting Out: Influence of an Acting Intervention on Cognition and Brain Function

行动：行动干预对认知和大脑功能的影响

基本信息

批准号：
8038225
负责人：
ARTHUR F. KRAMER
金额：
$ 46.91万
依托单位：
UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-03-01 至 2015-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8038225
关键词：
Acting Out Activities of Daily Living Adult Age Aging Area Arts Behavioral Brain Brain imaging Caring Cognition Cognitive Cognitive aging Communities Comprehension Control Groups Educational Intervention Effectiveness of Interventions Elderly Functional Imaging Functional Magnetic Resonance Imaging Funding Generations Goals Home environment Illinois Individual Instruction Intervention Intervention Studies Laboratories Life Low income Magnetic Resonance Imaging Measures Memory Participant Perception Performance Personal Satisfaction Population Populations at Risk Problem Solving Process Protocols documentation Psyche structure Research Research Personnel Resolution Structure System Techniques Testing Time Training Universities alternative treatment base behavior measurement bioimaging cost executive function experience foot improved indexing multi-component intervention neuroimaging novel processing speed professor programs tool

项目摘要

DESCRIPTION (provided by applicant): The long term objective of this project is to develop easily implemented multimodal interventions that can positively influence cognition, brain function, and well being of older adults. Two previously funded NIA studies conducted by our research team demonstrated the cognitive benefits of a novel, short-term intervention for older adults. Those studies consisted of four-week courses in the techniques used by professional actors to create lifelike characters, and resulted in gains on measures of recall, prose comprehension/memory, word generation, and problem-solving ability. In the first study, the participants were community-dwelling seniors. Improvements were measured against both no-treatment controls and alternative-treatment controls (art appreciation). The second study extended the findings to a far more at-risk population: adults who were almost a full decade older, less well educated, and who no longer lived in their own homes but in low income, continuing care facilities that were rarely able to offer specialized programs of mental stimulation. Once again, the benefits were demonstrated against no-treatment controls and an alternate intervention (musical performance). In the proposed present project we will substantially extend this research by investigating not just behavioral measures of improved cognition but also by examining changes in brain function and structure which result from acting instruction, as indexed by magnetic resonance imaging and functional magnetic resonance imaging. We will also extend our examination of the aspects of perception and cognition, with both laboratory tests and tests of everyday cognition, that are influenced by the acting intervention. We will also include control conditions that will enable us to discern the important mechanisms which underlie the benefits of our intervention on cognition and brain. Finally, we will examine whether changes in cognition and well- being attributed to the acting intervention persist over time. PUBLIC HEALTH RELEVANCE: Given the aging of our population, and indeed many populations across the world, there is a pressing need for practical, low-cost tools to promote healthy cognitive aging. This application significantly extends an intervention previously shown to improve, after a short period of time, a number of aspects of cognition and well being of older adults.

描述（由申请人提供）：该项目的长期目标是开发易于实施的多模式干预措施，这些干预措施可以积极影响认知，大脑功能以及老年人的健康。我们的研究小组进行的两项先前资助的NIA研究表明，新型老年人的短期干预措施的认知益处。这些研究包括专业演员用来创建栩栩如生角色的技术中的四周课程，并在召回，散文理解/记忆，单词产生和解决问题的能力的措施上取得了收益。在第一项研究中，参与者是社区居民的老年人。针对未处理控制和替代处理控制（ART GENSITION）测量了改进。第二项研究将调查结果扩展到了更多的高危人口：成年人将近十年的年龄较大，受过良好的教育，不再生活在自己的家中，而是在低收入中，持续的护理机构很少能够提供精神刺激的专业计划。再次证明了对无治疗控制和替代干预（音乐表现）的好处。在拟议的目前项目中，我们将不仅通过研究改善认知的行为度量来实质上扩展这项研究，而且还通过检查由Acting指导而导致的大脑功能和结构的变化，这是由磁共振成像和功能磁共振成像所索引的。我们还将通过实验室测试和对日常认知的测试进行对感知和认知方面的研究，这些测试受到行动干预的影响。我们还将包括控制条件，使我们能够辨别我们干预认知和大脑的好处的重要机制。最后，我们将研究认知和福祉的变化是否归因于行动干预随着时间的流逝持续存在。公共卫生相关性：鉴于我们人口的老龄化，甚至在世界各地的许多人群中，迫切需要实用，低成本的工具来促进健康的认知衰老。该应用显着扩展了先前显示的干预措施，在短时间后，这些应用程序改善了认知和老年人的福祉的许多方面。