Acting Out: Influence of an Acting Intervention on Cognition and Brain Function

行动：行动干预对认知和大脑功能的影响

基本信息

批准号：
8423324
负责人：
ARTHUR F. KRAMER
金额：
$ 41.3万
依托单位：
UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-03-01 至 2015-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8423324
关键词：
Acting Out Activities of Daily Living Adult Age Aging Area Arts Behavioral Brain Brain imaging Caring Cognition Cognitive Cognitive aging Communities Comprehension Control Groups Educational Intervention Effectiveness of Interventions Elderly Functional Imaging Functional Magnetic Resonance Imaging Funding Generations Goals Home environment Illinois Individual Instruction Intervention Intervention Studies Laboratories Life Low income Magnetic Resonance Imaging Measures Memory Participant Perception Performance Personal Satisfaction Population Populations at Risk Problem Solving Process Protocols documentation Psyche structure Research Research Personnel Resolution Structure System Techniques Testing Time Training Universities alternative treatment base behavior measurement bioimaging cost executive function experience foot improved indexing multi-component intervention neuroimaging novel processing speed professor programs public health relevance tool

项目摘要

DESCRIPTION (provided by applicant): The long term objective of this project is to develop easily implemented multimodal interventions that can positively influence cognition, brain function, and well being of older adults. Two previously funded NIA studies conducted by our research team demonstrated the cognitive benefits of a novel, short-term intervention for older adults. Those studies consisted of four-week courses in the techniques used by professional actors to create lifelike characters, and resulted in gains on measures of recall, prose comprehension/memory, word generation, and problem-solving ability. In the first study, the participants were community-dwelling seniors. Improvements were measured against both no-treatment controls and alternative-treatment controls (art appreciation). The second study extended the findings to a far more at-risk population: adults who were almost a full decade older, less well educated, and who no longer lived in their own homes but in low income, continuing care facilities that were rarely able to offer specialized programs of mental stimulation. Once again, the benefits were demonstrated against no-treatment controls and an alternate intervention (musical performance). In the proposed present project we will substantially extend this research by investigating not just behavioral measures of improved cognition but also by examining changes in brain function and structure which result from acting instruction, as indexed by magnetic resonance imaging and functional magnetic resonance imaging. We will also extend our examination of the aspects of perception and cognition, with both laboratory tests and tests of everyday cognition, that are influenced by the acting intervention. We will also include control conditions that will enable us to discern the important mechanisms which underlie the benefits of our intervention on cognition and brain. Finally, we will examine whether changes in cognition and well- being attributed to the acting intervention persist over time.

描述（由申请人提供）：该项目的长期目标是开发易于实施的多模式干预措施，可以对老年人的认知、大脑功能和福祉产生积极影响。我们的研究团队进行的两项先前资助的 NIA 研究证明了一种新颖的短期干预措施对老年人的认知益处。这些研究包括为期四周的课程，内容涉及专业演员用来塑造栩栩如生的角色的技巧，并在回忆、散文理解/记忆、单词生成和解决问题的能力方面取得了进展。在第一项研究中，参与者是社区老年人。对照无治疗对照和替代治疗对照（艺术欣赏）来衡量改善情况。第二项研究将研究结果扩展到了风险更高的人群：年龄几乎整整十岁、受教育程度较低的成年人，他们不再住在自己的家中，而是生活在低收入的持续护理机构中，而这些机构很少能够提供医疗服务。提供专门的精神刺激计划。再次证明了与不治疗对照和替代干预（音乐表演）相比的益处。在拟议的当前项目中，我们将通过不仅研究改善认知的行为测量，而且检查由动作指令引起的大脑功能和结构的变化（如磁共振成像和功能磁共振成像所索引）来大幅扩展这项研究。我们还将通过实验室测试和日常认知测试来扩展对感知和认知方面的检查，这些测试受到行为干预的影响。我们还将包括控制条件，使我们能够辨别我们干预认知和大脑的好处背后的重要机制。最后，我们将研究行动干预带来的认知和幸福感的变化是否会随着时间的推移而持续存在。