Novel Photon Counting Clinical CT Detectors

新型光子计数临床 CT 探测器

基本信息

批准号：
7482068
负责人：
WILLIAM C BARBER
金额：
$ 14.2万
依托单位：
DXRAY, INC.
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-04-01 至 2008-09-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7482068
关键词：
Address Algorithms Anodes Area Binding Calcified Calcium Ceramics Clinical Code Collaborations Compatible Computer software Computers Consumption Contrast Media Count Coupled Custom DAQ Data Detection Development Diagnostic radiologic examination Dimensions Discrimination Dose Electronics Encapsulated Fibrosis Floods Floor Gadolinium Goals Grant Histocompatibility Testing Image Imaging Phantoms Imaging Techniques Imaging technology Individual Iodine Lateral Literature Mammography Manufacturer Name Marketing Measures Mechanics Methods Mind Modeling Morphologic artifacts Motor Noise Numbers Object Attachment Operating System Output Patients Performance Phase Photons Physiologic pulse Polychlorinated Biphenyls Power Sources Printing Property Pulse taking Radiation Range Rate Reading Records Research Resolution Risk Roentgen Rays Running Sampling Scanning Semiconductors Side Signal Transduction Simulate Slice Small Business Funding Mechanisms Small Business Innovation Research Grant Solid Source Speed Staging Standards of Weights and Measures Surface System Technology Temperature Testing Thick Tissues Tube United States Universities Weight Width X-Ray Computed Tomography base bone cadmium telluride cold temperature commercialization cost data acquisition density design detector feeding improved irradiation new technology next generation novel physical property programs prototype reconstruction response simulation size soft tissue statistics tumor voltage

项目摘要

DESCRIPTION (provided by applicant): Photon counting detectors with energy binning can improve CT performance by counting and binning each x-ray detected. Photon counting x-ray detectors applied to mammography and radiography have shown a dose reduction of 40% to 400% while maintaining sufficient contrast for these applications. For use in CT these detectors are limited, due to an upper bound in terms of their maximum count rate, and advances in maximum count rate capabilities is needed. In order to overcome count rate limitations, new technological developments in reducing the size of application specific integrated circuits (ASICs) has been applied to reading out semiconductor detectors. These advancements, along with improvements to the cost and reliability of the compound semiconductor cadmium telluride (CdTe), allow us to develop a photon counting detector and read-out technology for CT. Therefore the overall goal of this Fast Track Phase I/Phase II proposal is to develop a photon counting CT detector with energy binning and read-out that is capable of producing energy resolved CT scan which can deliver less radiation dose and differentiate between tissue types.

描述（由申请人提供）：具有能量分级的光子计数探测器可以通过对检测到的每个 X 射线进行计数和分级来提高 CT 性能。应用于乳房 X 线摄影和放射线摄影的光子计数 X 射线探测器已显示出剂量减少了 40% 至 400%，同时保持了这些应用的足够对比度。对于 CT 中的使用，这些探测器由于其最大计数率存在上限而受到限制，并且需要提高最大计数率功能。为了克服计数率限制，减小专用集成电路（ASIC）尺寸的新技术发展已被应用于读出半导体探测器。这些进步，加上化合物半导体碲化镉 (CdTe) 成本和可靠性的改进，使我们能够开发出用于 CT 的光子计数探测器和读出技术。因此，快速通道一期/二期提案的总体目标是开发一种具有能量分级和读出功能的光子计数 CT 探测器，能够产生能量分辨 CT 扫描，从而提供更少的辐射剂量并区分组织类型。