UKY DENTAL COBRE: BIOINFORMATICS & BIOSTATISTICS CORE

英国牙科 COBRE：生物信息学

• 批准号: 8360728
• 负责人: Richard J. Kryscio
• 金额: $ 14.23万
• 依托单位: UNIVERSITY OF KENTUCKY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-01 至 2012-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8360728
• 关键词: Bioinformatics; Biometry; Biostatistics Core; Centers of Research Excellence; Confidentiality; Consultations; Data; Data Analyses; Data Quality; Databases; Dental; Development; Experimental Designs; Funding; Grant; Methodology; Monitor; National Center for Research Resources; Oral; Paper; Pilot Projects; Principal Investigator; Publications; Research; Research Design; Research Infrastructure; Research Personnel; Research Proposals; Resources; Sample Size; Secure; Security; Source; Students; Systemic disease; Training; United States National Institutes of Health; Work; base; cost; follow-up; graduate student; statistics

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The Biostatistics and Bioinformatics Core (BBC) will provide a centralized, secure database, statistical consultation on study design and data analysis, and bioinformatics support during development and implementation of the projects and pilot studies in the CBBO/SD. The specific aims of this BBC are: (1) Assist investigators in resolving issues related to experimental design, sample size determinations, and the statistical / bioinformatics analysis of data, (2) Create a centralized database to assure high quality data is collected (3) Maintain the integrity, confidentiality, and security of all data in compliance with all current regulatory statutes but at a minimum cost to the projects. (4) Provide periodic summaries of the database in clinically oriented projects to the Center Executive Committee to monitor subject recruitment and follow-up. (5) Participate in the training of graduate students, Certificate Students, postdoctoral researchers, and young investigators. (6) Develop new methodology in statistics and/or bioinformatics as needed in the CBBO/SD. (7) Collaborate with CBBO/SD investigators in preparing papers for publication (8) Work with investigators in developing competitive research proposals

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 生物统计学和生物信息学核心（BBC）将提供集中式，安全的数据库，研究设计和数据分析的统计咨询，以及在CBBO/SD中开发和实施项目和试点研究期间的生物信息学支持。 BBC的具体目的是： （1）协助研究人员解决与实验设计，样本量确定以及数据统计 /生物信息学分析有关的问题， （2）创建一个集中数据库，以确保收集高质量数据 （3）在所有当前的监管法规中，保持所有数据的完整性，机密性和安全性，但要对项目的最低成本。 （4）向中心执行委员会提供有关临床导向项目中数据库的定期摘要，以监视受试者招聘和随访。 （5）参加研究生，证书学生，博士后研究人员和年轻研究人员的培训。 （6）根据CBBO/SD中的需要开发统计和/或生物信息学的新方法。 （7）与CBBO/SD调查人员合作准备出版论文 （8）与研究人员合作制定竞争性研究建议