EFFECTS OF STRESSFUL EVENTS IN SINGLY- VS PAIR-HOUSED ADULT MALE MACAQUES

压力事件对单养与配对成年雄性猕猴的影响

• 批准号: 8172992
• 负责人: KATE CANFIELD BAKER
• 金额: $ 6.18万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8172992
• 关键词: Adult; Affect; Anesthesia procedures; Animals; Behavior; Behavioral; Buffers; Computer Retrieval of Information on Scientific Projects Database; Data; Data Collection; Devices; Enrollment; Frequencies; Funding; Grant; Housing; Implant; Individual; Institution; Laboratories; Long-Term Effects; Macaca; Macaca mulatta; Measures; Methods; Monkeys; Outcome; Personal Satisfaction; Phase; Physiological; Primates; Research; Research Personnel; Resources; Sampling; Source; Stressful Event; Telemetry; Time; United States National Institutes of Health; male; nonhuman primate; restraint; social; species typical behavior

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Introduction: Social housing for captive nonhuman primates has been shown to reduce the frequency of abnormal behavior and to increase species-typical behavior. In addition, previous research at the Tulane National Primate Research Center using male rhesus macaques implanted with telemetry devices has shown that physiological parameters correspond to the behavioral parameters of successful social introductions. The purpose of this ongoing study is to examine the long-term effects of social introduction by measuring, via physiological and behavioral means, the potential of social housing to act as a buffer to stressful events. Methods: The monkeys were first implanted with telemetry devices. They were initially housed singly, and during this phase, both behavioral and physiological data were collected during 30-minute focal animal samples. During this time, potentially stressful events that occurred as part of the monkeys' daily routine were documented with physiological and behavioral parameters. The monkeys were then paired, and once they were in settled social pairs, the data collection as described above was repeated. Twelve M. mulatta were enrolled on the study. Behavioral and physiological data have been collected on all subjects. Results/Discussion: When visually exposed to the restraint and anesthesia of another monkey in the room, monkeys that are pair housed show statistically significant reductions in rates of abnormal behavior. No statistically significant differences were seen when dominant and subordinate individuals were compared. The results of this study indicate that social buffering during stressful events can be considered an additional benefit to the well-being of socially-housed laboratory nonhuman primates. This is important in research because both physiological and behavioral parameters can affect the outcome of data during a study.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 简介：圈养非人类灵长类动物的社会住房已被证明可以减少异常行为的频率并增加物种典型的行为。 此外，杜兰国家灵长类研究中心之前使用植入遥测设备的雄性恒河猴进行的研究表明，生理参数与成功社交介绍的行为参数相对应。 这项正在进行的研究的目的是通过生理和行为手段测量社会住房作为压力事件缓冲的潜力，以检验社会引入的长期影响。 方法：首先给猴子植入遥测装置。 它们最初被单独饲养，在此阶段，在 30 分钟的焦点动物样本中收集行为和生理数据。 在此期间，猴子日常生活中发生的潜在压力事件被记录在生理和行为参数中。 然后将猴子配对，一旦它们形成稳定的社会配对，就重复上述数据收集。 十二名穆拉塔 (M. mulatta) 参加了这项研究。 已收集所有受试者的行为和生理数据。 结果/讨论：当在视觉上暴露于房间中另一只猴子的约束和麻醉时，配对饲养的猴子表现出异常行为率的统计显着降低。 当比较主导个体和从属个体时，没有发现统计学上的显着差异。 这项研究的结果表明，压力事件期间的社会缓冲可以被认为是对社会饲养的实验室非人类灵长类动物的福祉的额外好处。 这在研究中很重要，因为生理和行为参数都会影响研究期间的数据结果。