Cancer Epidemiology

癌症流行病学

• 批准号: 7900745
• 负责人: CHARLES F LYNCH
• 金额: $ 2.25万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7900745
• 关键词: Address; Aging; Agriculture; Area; Biology of Aging; Cancer Center; Cancer Center Support Grant; Cancer Control; Cancer Etiology; Cancer Patient; Cancer Survivor; Chemoprevention; Clinical; Clinical Research; Cohort Studies; Collaborations; Databases; Development Plans; Dose; Elderly; Epidemiologic Studies; Epidemiology; Etiology; Evaluation; Farming environment; Focus Groups; Fostering; Funding; Generations; Genetic; Goals; Grant; Head and Neck Cancer; Health; Health Personnel; Health Services; Health Services Research; Health system; Heart Diseases; Human Papillomavirus; Incidence; Insurance; Interdisciplinary Study; Iowa; Joints; Knowledge; Lead; Lesion; Link; Lymphoma; Malignant Neoplasms; Malignant neoplasm of lung; Malignant neoplasm of ovary; Morbidity - disease rate; Odds Ratio; Outcome; Pathogenesis; Pattern; Peer Review; Pesticides; Pharmacologic Substance; Pharmacology; Premalignant; Preventive; Public Health; Quality of life; Radon; Recommendation; Reporting; Reproduction spores; Research; Research Personnel; Risk; Rural; Schools; Services; Strategic Planning; Stress; Treatment Efficacy; Women' s Health; cancer care; cancer epidemiology; cancer prevention; chemotherapy; college; cytokine; effectiveness research; epidemiologic data; gene environment interaction; hormone therapy; hospice environment; improved; insight; interest; member; neoplasm registry; novel; prevent; programs; response; voluntary health organization

Research in the Cancer Epidemiology Program uses epidemiologic data to enhance our understanding of cancer incidence and therapy, and to explore how we can use this information to decrease cancer incidence and improve outcome. The overall goal of the members of this program is to perform epidemiologic research that will provide additional knowledge for educational and service-oriented activities aimed at decreasing cancer incidence, increasing survival, and improving quality of life. There are five major overlapping focus areas within the umbrella of the Program's research. Theme 1 - Cancer etiology Theme 2 - Cancer health services and outcomes Theme 3 - The epidemiology of head and neck cancer Theme 4 - Cancer prevention and control Theme 5 - Cancer and aging. Examples of major accomplishments of the Cancer Epidemiology Program over the past funding period include (a) description of novel findings regarding pesticides and cancer from the Agricultural Health Study cohort, (b) reporting of stronger dose-response odds ratios for residential radon and lung cancer likely due to more accurate exposure assessment, (c) the Women's Health Initiative findings on hormone therapy that concluded with a recommendation that hormone therapy not be taken to prevent heart disease, and (d) the discovery that stress mechanisms are related to angiogenic cytokines in ovarian cancer. There are numerous past and present productive collaborations both between members of the Program, and with members of other Cancer Center Programs. Current examples include the lung cancer care outcomes/surveillance consortium study, the Lymphoma SPORE, the Cancer and Aging P20, the Health Effectiveness Research Center, studies of human papillomavirus and cancer, the Iowa Comprehensive Cancer Control Consortium, and the Iowa Cancer Registry. The program consists of 26 members from 13 departments and 5 colleges. Current, peer-reviewed, cancer-related research, annual direct funding for this program totals $6,020,366 with $2,334,604 coming from the NCI.

癌症流行病学计划中的研究使用流行病学数据来增强我们对 癌症的发病率和治疗，并探索我们如何使用此信息降低癌症的发生率 并改善结果。该计划成员的总体目标是进行流行病学研究 这将为旨在减少教育和服务的活动提供更多知识 癌症发病率，增加生存和改善生活质量。有五个重叠的重点 该计划研究的保护区内。 主题1-癌症病因 主题2-癌症健康服务和成果 主题3-头颈癌的流行病学 主题4-预防癌症和控制 主题5-癌症和衰老。 过去资金期间癌症流行病学计划的主要成就的例子 包括（a）农业健康研究中有关农药和癌症的新发现的描述 队列，（b）报告剂量响应较强的剂量 - 响应优势比可能是由于 更准确的暴露评估，（c）妇女健康倡议的结果，关于激素治疗的结果 最后提出了不采取激素治疗以预防心脏病的建议，（d） 发现压力机制与卵巢癌中的血管生成细胞因子有关。有很多 该计划成员之间以及与 其他癌症中心计划。当前的例子包括肺癌护理结果/监视 财团研究，淋巴瘤孢子，癌症和衰老P20，健康有效性研究 中心，人类乳头瘤病毒和癌症的研究，爱荷华州综合癌症控制联盟， 和爱荷华州癌症注册表。该计划由来自13个系和5所大学的26名成员组成。 目前，同行评审，与癌症相关的研究，该计划的年度直接资金总计为6,020,366美元 $ 2,334,604来自NCI。