Alcohol use, survival, and quality of life at older ages: A prospective study.

老年人的饮酒、生存和生活质量：一项前瞻性研究。

• 批准号: 7788919
• 负责人: MARK S. KAPLAN
• 金额: $ 19.09万
• 依托单位: PORTLAND STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-02-15 至 2012-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7788919
• 关键词: Abstinence; Address; Adult; Affect; Age; Aging; Alcohol consumption; Alcohols; Benefits and Risks; Birth; Canada; Cardiovascular system; Chronic; Cirrhosis; Consumption; Country; Cross-Sectional Studies; Data; Data Set; Databases; Deltastab; Development; Diet; Education; Elderly; Etiology; Frequencies; Gender; Graph; Guidelines; Health; Health Personnel; Health Policy; Health Status; Health Surveys; Healthcare; Hospitalization; Hypertension; Impaired health; Income; Individual; Injury; Institutionalization; Intercept; Life; Long-Term Care; Longevity; Measures; Mental Health; Morbidity - disease rate; NIH Program Announcements; National Institute on Aging; National Institute on Alcohol Abuse and Alcoholism; Older Population; Outcome; Participant; Patient Self-Report; Pattern; Pharmaceutical Preparations; Physical activity; Play; Policy Analysis; Population; Prospective Studies; Public Health; Quality of life; Reporting; Research Design; Research Personnel; Research Project Grants; Resources; Risk; Risk Factors; Role; Sampling; Shapes; Smoking; Social Network; Surveys; Time; United States National Institutes of Health; Update; Variant; Woman; Work; Writing; addiction; age related; aged; aging population; alcohol use initiation; base; binge drinker; binge drinking; body system; cohort; drinking; drinking behavior; emerging adult; falls; follow-up; health care service utilization; health related quality of life; longitudinal analysis; men; mortality; population health; programs; public health relevance; public policy on alcohol; response; young adult

DESCRIPTION (provided by applicant): This application is a revision of R21 AG033796-01, which was most recently reviewed by ZRG1 HOP-L (90) in October 2008. The revision clarifies the conceptual component and research design, and adds Dr. Norman Giesbrecht of the Centre for Addiction & Mental Health as a consultant on provincial alcohol policies and the selection of instrumental variables. Little is known about longitudinal patterns of alcohol use among older adults. Moreover, there are few if any data regarding associations between longitudinal measures of alcohol consumption and morbidity in an aging population. This information is highly relevant to public health because most older adults consume alcohol. However, it is unclear what (if any) amounts of alcohol are safe for routine use in this population. For example, the National Institute on Alcohol Abuse and Alcoholism suggests that for older individuals, alcohol use should be no more than one drink per day. Conversely, researchers supported and/or employed by the National Institute on Aging recently suggested that the alcohol use guidelines should be the same for older as for younger adults (no more than two drinks per day). Needed now is evidence to inform development of guidelines regarding alcohol use for older individuals. Inconveniently, many if not most studies examining relationships between alcohol consumption and mortality are based on drinking behavior reported at baseline. Few projects have used patterns of alcohol consumption over time to predict mortality. Moreover, there is little if any information about connections between longitudinal patterns of alcohol use and measures of morbidity such as health-related quality of life or health care utilization. It has also been difficult to address possible reverse causation in which health status can influence alcohol consumption. The proposed project will address these issues by analyzing the Canadian longitudinal National Population Health Survey. This nationally representative data set includes twelve years of detailed self-reported information about alcohol use. The database also addresses diet, physical activity, and smoking as well as numerous other health determinants. Each two-year cycle of the survey includes health-related quality of life information as well as data on hospitalization and long-term care placement. This project will use the longitudinal data to (a) describe patterns of alcohol consumption over time among participants who were 50 years or older at baseline, (b) assess the relationships between longitudinal alcohol use and self-reported hospitalization, (c) analyze associations between longitudinal drinking patterns and long-term care placement, (d) study connections between longitudinal drinking patterns and health-related quality of life, and (e) examine relationships between longitudinal alcohol use patterns and mortality. The results will provide important information about relationships between longitudinal alcohol consumption and health-related outcomes for older adults. These results, in turn, can be used to develop guidelines regarding alcohol use in an older population. PUBLIC HEALTH RELEVANCE: This project will use data from the Canadian longitudinal National Population Health Survey to examine the relationship between patterns of alcohol consumption and health outcomes, including institutionalization and mortality among adults aged 50 and older. Information from this study will be of considerable relevance to public health as guidelines for alcohol use among older adults are updated.

描述（由申请人提供）：此申请是R21 AG033796-01的修订版，最近由ZRG1 Hop-L（90）于2008年10月对其进行了审查。该修订版阐明了概念上的组成部分和研究设计，并添加了Norman Giesbrecht博士成瘾中心和精神健康的顾问，作为一项顾问的顾问，该顾问是对省级酒精葡萄酒和选择的顾问。关于老年人饮酒的纵向模式知之甚少。此外，在老龄化人群中，几乎没有关于饮酒纵向测量与发病率之间的关联的数据。该信息与公共卫生高度相关，因为大多数老年人都会食用酒精。但是，目前尚不清楚该人群中常规使用的酒精（如果有的话）是安全的。例如，美国国家酒精滥用和酒精中毒研究所表明，对于年长的人来说，饮酒每天不应超过一杯饮料。相反，由美国国家老化研究所（National Institute on Nation）支持和/或雇用的研究人员最近建议，对于年长的年轻人，酒精使用指南应相同（每天不超过两杯饮料）。现在所需的证据是为了开发有关老年人饮酒准则的制定的证据。不方便的是，许多研究饮酒和死亡率之间的关系的许多研究是基于基线报道的饮酒行为。随着时间的流逝，很少有项目使用饮酒模式来预测死亡率。此外，几乎没有关于酒精使用纵向模式与健康相关的生活质量或医疗保健利用等发病率的措施之间的联系。也很难解决健康状况会影响饮酒的可能逆转因果关系。拟议的项目将通过分析加拿大纵向国家人口健康调查来解决这些问题。这个国家代表性的数据集包括有关饮酒的详细自我报告的详细自我报告的信息。该数据库还解决饮食，体育锻炼和吸烟以及许多其他健康决定因素。调查的每个两年周期都包括与健康相关的生活质量信息以及有关住院和长期护理安置的数据。 This project will use the longitudinal data to (a) describe patterns of alcohol consumption over time among participants who were 50 years or older at baseline, (b) assess the relationships between longitudinal alcohol use and self-reported hospitalization, (c) analyze associations between longitudinal drinking patterns and long-term care placement, (d) study connections between longitudinal drinking patterns and health-related quality of life, and (e) examine relationships between longitudinal alcohol use patterns和死亡率。结果将提供有关纵向饮酒与老年人与健康相关的结果之间关系的重要信息。反过来，这些结果可用于制定有关老年人群中饮酒的准则。 公共卫生相关性：该项目将使用加拿大纵向全国人口健康调查的数据来研究酒精消费模式与健康结果的关系，包括50岁及以上成年人的制度化和死亡率。这项研究的信息将与公共卫生相关，因为更新了老年人饮酒准则。