CSHL Course on C. elegans

CSHL 线虫课程

基本信息

批准号：
7285314
负责人：
TERRI I. GRODZICKER
金额：
$ 7.63万
依托单位：
COLD SPRING HARBOR LABORATORY
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
起止时间：
1998-08-01 至 2011-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7285314
关键词：
Adult Affect Alleles American Brain Tumor Association Anatomy Animals Antibodies Area Arts Bacteriology Bacteriophages Basic Science Behavioral Biochemical Pathway Biochemistry Bioinformatics Biological Biological Models Biological Process Biology Boston Botany Brain Neoplasms C. elegans genome Caenorhabditis elegans California Cell division Cell physiology Cells Cellular biology Class Cloning Cods Collaborations Communities Computer software Computers Coupled Crystallography DNA Microarray Chip DNA Microarray format Data Set Development Developmental Biology Developmental Cell Biology Discipline Drosophila genus Educational Curriculum Educational process of instructing Educational workshop Embryo Embryology Enrollment Ensure Evolution Exposure to Faculty Fibroblast Growth Factor Foundations Freezing Funding Gene Expression Generations Genes Genetic Genetic Complementation Test Genetic Recombination Genetic Techniques Genome Genomics Germany Grant Green Fluorescent Proteins Growth Histocompatibility Testing Home environment Human Human Genome Human Genome Project Image Immersion Investigative Technique In Situ Hybridization Individual Influentials Informatics Injection of therapeutic agent Institutes Institution Instruction Insulin Signaling Pathway International Ion Channel Japan Journals Knock-out Knowledge Laboratories Laboratory Study Lead Learning Life Life Cycle Stages Liquid substance Long Island Maintenance Malignant neoplasm of brain Maps Medical Mentors Methodology Methods MicroRNAs Microbial Genetics Microinjections Molecular Molecular Biology Molecular Cloning Molecular Genetics Mus Muscle function Mutagenesis Mutagens Mutation National Cancer Institute National Institute of Child Health and Human Development National Institute of Mental Health Natural History Natural Immunity Nature Nematoda Nervous system structure Neurobiology Neurons Neurosciences Normal Cell Numbers Organism Paper Participant Pathology Pathway interactions Pattern Peptides Phage Display Pharmaceutical Preparations Pharmacology Phenotype Philosophy Physical Map of the Human Genome Physiology Plants Policies Polymerase Chain Reaction Positioning Attribute Postdoctoral Fellow Principal Investigator Process Progress Reports Proteins Proteomics Publishing RNA Interference Recording of previous events Reporter Research Research Infrastructure Research Institute Research Personnel Research Project Grants Research Training Roentgen Rays Running Schools Science Scientist Screening procedure Seminal Senior Scientist Sensory Series Side Signal Transduction Single Nucleotide Polymorphism Map Somatic Cell Speed Staging Staining method Stains Stem cells Structure Students System Techniques Technology Tennessee Tern Time Title Training Transgenic Organisms Universities Update Viral Genes Virus Cultivation Vision Week Work Writing Xenopus Yeasts Zoology abstracting axon guidance bacterial genetics base cellular imaging comparative computational neuroscience concept day design experience falls feeding gene function gene replacement genetic analysis genome sequencing human disease immunocytochemistry innovation instructor interest lecturer lectures literature survey migration mouse model mutant neoplastic cell neuromechanism novel strategies physical mapping positional cloning programs protein purification relating to nervous system research study skills statistics stem structural biology tool yeast genetics

项目摘要

DESCRIPTION (provided by applicant): The proposed Cold Spring Harbor Laboratory Course on C. elegans is to be held July 27 - August 14, 2006, 2007, 2008, 2009, and 2010. This is an intensive three-week summer course aiming to introduce students to the practical aspects of using C. elegans as an experimental system. The program seeks to provide established researchers, postdoctoral fellows, and senior graduate students with limited or no previous C. elegans experience with enough theoretical and practical knowledge to allow them to productively introduce and use C. elegans as a tool in their home laboratories. Sessions are planned to cover the following topics: Worm Pushing; Anatomy and Development; Forward Genetics (mutagenesis, complementation, mapping); Generation of Transgenics; Analysis of Expression Patterns; Reverse Genetics (knockouts, RNA interference); and Worm Biochemistry. The course is taught by an energetic faculty team which is fully active in, and has made significant contributions to, the areas under study. This ensures that the newest techniques and ideas will be presented. The course's curriculum will continue to be reviewed and updated annually so that it reflects the recent advances in the fields under study. The faculty is supplemented by a series of seminar speakers who will present current research and application of advanced techniques in their fields of expertise.

说明（由申请人提供）：拟议的冷泉港线虫实验室课程将于 2006 年、2007 年、2008 年、2009 年和 2010 年 7 月 27 日至 8 月 14 日举行。这是一个为期三周的强化夏季课程，旨在向学生介绍使用秀丽隐杆线虫作为实验系统的实际情况。该计划旨在为那些缺乏或没有线虫经验的知名研究人员、博士后研究员和高年级研究生提供足够的理论和实践知识，使他们能够在家庭实验室中高效地引入和使用线虫作为工具。会议计划涵盖以下主题：蠕虫推送；解剖与发育；正向遗传学（诱变、互补、作图）；转基因的产生；表达模式分析；反向遗传学（基因敲除、RNA 干扰）；和蠕虫生物化学。该课程由一支充满活力的教师团队教授，他们在所研究的领域非常活跃，并做出了重大贡献。这确保了展示最新的技术和想法。该课程的课程将继续每年进行审查和更新，以反映所研究领域的最新进展。该学院还辅以一系列研讨会演讲者，他们将介绍其专业领域中先进技术的当前研究和应用。