CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCH

CTSA 儿科研究基础设施

• 批准号: 7719777
• 负责人: JULIANNE L IMPERATO-MCGINLEY
• 金额: $ 183.07万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-06-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7719777
• 关键词: Pediatric Research; Research Infrastructure

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The development of the Clinical and Translational Science Center (CTSC) fulfills the mission to advance the nation's clinical research enterprise of moving translational research seamlessly from bench to bedside and to the community. The Center represents our vision to deliver the vast knowledge of recent biomedical advances to clinical application for meaningful healthcare practices and to nurture multidisciplinary translational research education and training. The CTSC has been designed to capture the collective of intellectual capital, cutting-edge resources and diverse patient base of partnering institutions and to integrate them for maximum translational research benefits. As lead institution, Weill Cornell Medical Center (WCMC) will serve as an academic home through which essential resources, technological tools and education programs can be efficiently shared and managed. The partner institutions comprising the CTSC are also neighbors located on York Avenue. Within the immediate area are: WCMC, including Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences and the Weill Cornell Campus of NewYork-Presbyterian Hospital; Memorial Sloan-Kettering Cancer Center; and the Hospital for Special Surgery. In close proximity on the East Side of Manhattan are: Hunter College School of Nursing, Hunter College Center for the Study of Gene Structure and Function/Research Center for Minority Institutions and the Cornell University Cooperative Extension in New York City. The resulting cluster of institutions forms a unique and cohesive biomedical complex fulfilling the NIH roadmap initiative of breaking-down institutional and disciplinary silos to accelerate translational research. Separately, the partner institutions are superb centers of intellectual and academic excellence, thus their integration into the CTSC will harness their distinctive characteristics and hasten clinical and translational research breakthroughs for improved patient care. The trans-institutional governance structure outlined in this application and supplemented by a comprehensive systems-based evaluation process are important in overcoming bureaucracies and barriers. New initiatives were sculpted and programs with a history of collaboration between partners were broadened and restructured. The key elements of the CTSC are: 1) development of novel clinical and translational methodologies; 2) pilot and collaborative translational and clinical studies; 3) biomedical informatics; 4) design, biostatistics and clinical research ethics; 5) regulatory knowledge and support; 6) participant and clinical interaction resources; 7) community engagement and research; 8) translational technologies and resources; 9) research education, training and career development; and 10) other program functions. The CTSC is a vital link between the academic, research and clinical practice functions of partner institutions and will provide an important continuum in translational research.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 临床和转化科学中心（CTSC）的发展履行了使国家临床研究企业促进翻译研究的使命，该企业将翻译研究从长凳转移到床边和社区。该中心代表了我们的愿景，即将最近的生物医学进步了解有意义的医疗保健实践应用，并培养多学科翻译研究教育和培训。 CTSC旨在捕获合作机构的智力资本，尖端资源和多样化的患者基础的集体，并将其整合起来，以获得最大的转化研究益处。作为领导机构，Weill Cornell医疗中心（WCMC）将作为一个学术住所，可以通过该家居有效地共享和管理基本资源，技术工具和教育计划。由CTSC组成的合作机构也是约克大街的邻居。在附近的地区是：WCMC，包括Weill Cornell医学院，Weill Cornell医学科学研究生院和Newyork-Presbyterian Hospital的Weill Cornell校园；纪念斯隆 - 凯特林癌症中心；和特殊手术医院。曼哈顿东侧附近的近距离是：猎人学院护理学院，亨特学院基因结构和职能研究中心/少数民族机构的研究中心和纽约市康奈尔大学合作扩展。由此产生的机构群形成了一个独特而有凝聚力的生物医学综合体，以符合NIH路线图的倡议，该计划是破坏制度和纪律筒仓，以加速转化研究。另外，合作伙伴机构是智力和学术卓越的出色中心，因此它们融入CTSC将利用其独特的特征，并加快临床和转化研究突破，以改善患者护理。本应用中概述的跨机构治理结构并补充了基于系统的评估过程，这对于克服官僚机构和障碍很重要。雕刻了新的计划，并扩大了合作伙伴之间合作历史的计划。 CTSC的关键要素是：1）新型临床和转化方法的发展； 2）试点和协作转化和临床研究； 3）生物医学信息学； 4）设计，生物统计学和临床​​研究伦理； 5）监管知识和支持； 6）参与者和临床互动资源； 7）社区参与和研究； 8）翻译技术和资源； 9）研究教育，培训和职业发展； 10）其他程序功能。 CTSC是合作机构的学术，研究和临床实践功能之间的重要联系，并将在翻译研究中提供重要的连续性。