Secondary Prevention of Alcohol Dependence and Depression Among College Students

大学生酒精依赖和抑郁症的二级预防

基本信息

批准号：
7504010
负责人：
TIBOR P. PALFAI
金额：
$ 19.3万
依托单位：
BOSTON UNIVERSITY (CHARLES RIVER CAMPUS)
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-09-30 至 2010-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7504010
关键词：
Address Affective Alcohol abuse Alcohol consumption Alcohol dependence Alcohols Characteristics Classification Cognition Cognitive Condition Counseling Development Disease Distress Effectiveness of Interventions Exhibits Facility Construction Funding Category Feedback Frequencies Functional disorder Goals Health Heavy Drinking Intervention Maintenance Major Depressive Disorder Manuals Measures Mediator of activation protein Mental Depression Mental disorders Modification Motivation National Institute on Alcohol Abuse and Alcoholism Numbers Outcome Participant Personal Satisfaction Phase Pilot Projects Prevention Prevention approach Procedures Process Randomized Controlled Trials Rate Recurrence Risk Role Secondary Prevention Source Staging Students Symptoms System Testing Training Treatment Efficacy Week Work alcohol related problem base binge drinking day depressive symptoms disability disorder risk drinking drinking behavior experience follow-up method development pilot trial prevent single episode major depressive disorder size subclinical depression university student

项目摘要

DESCRIPTION (provided by applicant): Project Summary: Alcohol dependence and major depression represent two major sources of distress and disability among college students. Risks for the development of these disorders include hazardous drinking and elevated depressive symptoms respectively, both of which are experienced by a large proportion of college students and place them at risk for a variety of negative academic and interpersonal consequences. Hazardous drinking and elevated depressive symptoms not only increase the risk for the development of alcohol dependence and major depression but also have reciprocal influences on one another in the development, maintenance, and recurrence of these disorders. Finally, hazardous drinking students with elevated subclinical depression symptoms exhibit distinct cognitive motivational characteristics that may influence their ability to change. Given the frequent co-occurrence of elevated depressive symptoms and hazardous drinking, there are a number of advantages to addressing both of the issues in an integrated intervention. The current project seeks to develop a short-term (3-session) intervention to address these objectives. Specifically, this proposal seeks to: (1) develop an integrated short-term secondary prevention approach for alcohol dependence and major depression for college students at risk for these disorders, and (2) conduct a pilot trial to determine effect size estimates of the efficacy of the intervention. During the first phase (Stage 1A) the intervention will be developed and pilot tested with 8 hazardous drinking college students who exhibit mild to moderate depressive symptoms. For the pilot trial (Stage1B), participants will be assigned to either a short-term intervention that is based on systematic motivational counseling (Cox & Klinger, 2004) or an Assessment Only control condition. Alcohol outcomes, depressive symptoms, and hypothesized change processes will be assessed at baseline, 3 and 6 months. Results of this work will provide the basis for a randomized controlled trial to examine the efficacy of this new intervention to prevent the development of alcohol dependence and major depression.

描述（由申请人提供）：项目摘要：酒精依赖和重度抑郁症是大学生痛苦和残疾的两个主要来源。形成这些疾病的风险分别包括危险饮酒和抑郁症状加重，大部分大学生都经历过这两种情况，并使他们面临各种负面学术和人际关系后果的风险。有害饮酒和抑郁症状加重不仅会增加酒精依赖和重度抑郁症的风险，而且还会在这些疾病的发生、维持和复发中相互影响。最后，具有亚临床抑郁症状的危险饮酒学生表现出独特的认知动机特征，可能会影响他们的改变能力。鉴于抑郁症状加重和危险饮酒经常同时发生，通过综合干预解决这两个问题有很多好处。当前的项目旨在制定短期（3 次）干预措施来实现这些目标。具体来说，该提案旨在：（1）为有酒精依赖和重度抑郁症风险的大学生开发一种综合的短期二级预防方法，以及（2）进行试点试验以确定疗效的效应大小估计的干预。在第一阶段（第 1A 阶段），将制定干预措施并在 8 名表现出轻度至中度抑郁症状的危险饮酒大学生中进行试点测试。对于试点试验（Stage1B），参与者将被分配到基于系统动机咨询的短期干预（Cox＆Klinger，2004）或仅评估控制条件。将在基线、3 个月和 6 个月时评估酒精结果、抑郁症状和假设的变化过程。这项工作的结果将为随机对照试验提供基础，以检验这种新干预措施预防酒精依赖和重度抑郁症发展的功效。