CWRU Clinical Vision Research Initiative

CWRU 临床视觉研究计划

• 批准号: 7386570
• 负责人: JONATHAN H LASS
• 金额: $ 14.56万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7386570
• 关键词: Award; Basic Science; Biometry; Cancer Center Support Grant; Chairperson; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Country; Data; Data Analyses; Data Coordinating Center; Development; Doctor of Medicine; Environment; Exploratory/Developmental Grant for Diagnostic Cancer Imaging; Goals; Grant; Hospitals; Information Resources; Medical center; Ophthalmology; Participant; Reporting; Research; Research Activity; Research Design; Research Personnel; Resources; Training; Universities; University Hospitals; Vision research; base; design; interest; programs; ranpirnase; research and development; vision science

DESCRIPTION (provided by applicant): This R21 Clinical Vision Research Development Award is designed to enhance the clinical research activities and capabilities of investigators in the Visual Sciences Research Center (VSRC) at Case Western Reserve University (CWRU). The CWRU VSRC, based in the Department of Ophthalmology, encompasses over 30 vision science researchers, 12 basic and clinical departments at CWRU, and 3 affiliated hospitals. The VSRC has an already established and excellent basic science research program as evidenced by 17 current R01 and R03 awards, a P30 Core Grant and T32 Training Grant. The next goal of the VSRC is to expand and strengthen resources to establish a strong clinical vision research program. This R21 award will allow for the expansion of the VSRC Clinical Research Unit and the creation of a VSRC Biostatistics Unit, two resources critical to the continued development of clinical vision research at CWRU. Under the direction of Jonathan Lass, M.D., PI of this proposed project and the current P30 Core Grant, Director of the VSRC, and Chairman of the CWRU Department of Ophthalmology, our specific aims are as follows: 1) expand the resources, knowledge, and staff of our existing Clinical Research Unit, 2) establish a Biostatistics Unit which will be self sufficient in serving all the study design, data analysis, and data reporting needs of our clinical investigators, and 3) ultimately establish data coordinating center capabilities and activities. Together with a strong basic science program and an expanding clinical science program made possible through this R21 award, we seek to place the CWRU VSRC as one of the leading visual sciences research centers in this country.

描述（由申请人提供）：R21 临床视觉研究开发奖旨在增强凯斯西储大学 (CWRU) 视觉科学研究中心 (VSRC) 研究人员的临床研究活动和能力。 CWRU VSRC 位于眼科，拥有 30 多名视觉科学研究人员、CWRU 12 个基础和临床科室以及 3 家附属医院。 VSRC 拥有已经建立的优秀基础科学研究项目，目前有 17 个 R01 和 R03 奖项、P30 核心补助金和 T32 培训补助金证明了这一点。 VSRC 的下一个目标是扩大和加强资源，以建立强大的临床视觉研究项目。该 R21 奖项将允许扩大 VSRC 临床研究单位并创建 VSRC 生物统计单位，这两项资源对于 CWRU 临床视觉研究的持续发展至关重要。 在该拟议项目的 PI 医学博士 Jonathan Lass 和现任 P30 核心资助者、VSRC 主任兼 CWRU 眼科系主任的指导下，我们的具体目标如下：1）扩大资源、知识、以及我们现有临床研究部门的工作人员，2) 建立一个生物统计部门，该部门将能够自给自足地满足我们临床研究人员的所有研究设计、数据分析和数据报告需求，以及 3) 最终建立数据协调中心的能力和活动。通过 R21 奖项，加上强大的基础科学项目和不断扩大的临床科学项目，我们力求将 CWRU VSRC 打造成美国领先的视觉科学研究中心之一。

项目成果

Predictive factors for corneal infiltrates with continuous wear of silicone hydrogel contact lenses.

• DOI: 10.1001/archopht.125.4.488
• 发表时间: 2007-04
• 期刊: Archives of ophthalmology
• 作者: L. Szczotka-Flynn;S. Debanne;V. Cheruvu;B. Long;S. Dillehay;J. Barr;P. Bergenske;P. Donshik

Descemet's stripping automated endothelial keratoplasty: three-year graft and endothelial cell survival compared with penetrating keratoplasty.

• DOI: 10.1016/j.ophtha.2012.08.007
• 发表时间: 2013-02
• 期刊: Ophthalmology
• 影响因子: 13.7
• 作者: Price MO;Gorovoy M;Price FW Jr;Benetz BA;Menegay HJ;Lass JH
• 通讯作者: Lass JH