A SIEMENS MAGNETOM TRIO 3 TESLA MRI SYSTEM: AD, AUTISM SD, DEPRESSION, MCI

西门子 MAGNETOM TRIO 3 TESLA MRI 系统：AD、自闭症 SD、抑郁症、MCI

• 批准号: 7335049
• 负责人: BRUCE R ROSEN
• 金额: $ 9万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7335049
• 关键词: autism; bioimaging /biomedical imaging; brain; brain mapping; choice; depression; functional magnetic resonance imaging; hospitals; image processing; lead

This subproject is one of many research subprojects utilizing the resources provided by a Shared Instrumentation Grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the grant, which is not necessarily the institution for the investigator. DESCRIPTION (provided by applicant): The Martinos Center for Biomedical Imaging is a leading imaging resource located at the Massachusetts General Hospital. The mission of the Center is to develop and apply innovative biomedical imaging technologies to improve understanding of the pathophysiology and treatment of disease, and as a window to the function of the mind and brain. The Center provides state-of-the-art imaging technologies including MRI, MEG, PET, optical imaging, and advanced image-processing capabilities to hundreds of investigators worldwide. While the Center currently operates two 3 Tesla MRI systems (Siemens MAGNETOM Allegra and Trio), the recent explosion in the use of high field MRI for functional brain mapping has led to a demand for these resources that exceeds our present ability to accommodate. Our 3T systems are now shared by more than seventy investigators whose productivity is greatly diminished by the insufficient availability of imaging time. The goal of this proposal is to obtain partial funding for a Siemens MAGNETOM 'TIM' Trio 3 Tesla MR system for the Martinos Center resource. The proposed system will alleviate overcrowding on the present systems allowing currently funded investigators sufficient imaging time to accomplish their research goals. Features of the Trio that make it our system of choice include a large patient bore, a wide range of RF coils (including multi-channel array coils) that provide outstanding sensitivity, its speed of image encoding which greatly reduces image susceptibility artifact, excellent gradient linearity enabling a range of imaging protocols unfeasible on other systems, and the ability to perform imaging of the body as well as the brain. An additional Siemens system, will provide other benefits as well including flexibility of scheduling and easy portability of pulse sequences across magnets, familiarity with the programming and user interface, and compatibility with our ongoing instrumentation development efforts. This badly needed shared instrument will enhance the imaging activities of the many PHS supported research programs at the Martinos Center.

该子项目是利用 NIH/NCRR 资助的共享仪器补助金提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中出现。列出的机构是资助机构，不一定是研究者的机构。描述（由申请人提供）：马蒂诺斯生物医学成像中心是位于马萨诸塞州总医院的领先成像资源。该中心的使命是开发和应用创新的生物医学成像技术，以提高对疾病病理生理学和治疗的理解，并作为了解精神和大脑功能的窗口。该中心为全球数百名研究人员提供最先进的成像技术，包括 MRI、MEG、PET、光学成像和先进的图像处理能力。虽然该中心目前运行着两台 3 Tesla MRI 系统（西门子 MAGNETOM Allegra 和 Trio），但最近高场 MRI 在功能性大脑绘图中的使用激增，导致对这些资源的需求超出了我们目前的容纳能力。我们的 3T 系统现在由 70 多名研究人员共享，他们的工作效率因成像时间不足而大大降低。该提案的目标是为 Martinos 中心资源的西门子 MAGNETOM“TIM”Trio 3 Tesla MR 系统获得部分资金。拟议的系统将缓解现有系统的过度拥挤，使目前资助的研究人员有足够的成像时间来完成他们的研究目标。 Trio 的特点使其成为我们选择的系统，包括较大的患者孔径、提供出色灵敏度的各种射频线圈（包括多通道阵列线圈）、可大大降低图像敏感性伪影的图像编码速度、出色的梯度线性度支持一系列在其他系统上不可行的成像协议，以及对身体和大脑进行成像的能力。额外的西门子系统还将提供其他好处，包括调度的灵活性和跨磁体的脉冲序列的轻松移植性、熟悉编程和用户界面以及与我们正在进行的仪器开发工作的兼容性。这种急需的共享仪器将增强马蒂诺斯中心许多 PHS 支持的研究项目的成像活动。