NEPHROLOGY AND HYPERTENSION TRAINING GRANT

肾脏病学和高血压培训补助金

• 批准号: 7501384
• 负责人: CHRISTOPHER S WILCOX
• 金额: $ 16.45万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7501384
• 关键词: Grant; Hypertension; Nephrology; Training

DESCRIPTION (provided by applicant): This is a proposal for a research training program for post-doctoral trainees in Nephrology and Hypertension. The goal is to prepare physicians and scientists to undertake independent investigation in renal and hypertensive disorders and in the basic biology which underlies normal and aberrant kidney function or blood pressure regulation. We emphasize application of cutting edge basic research techniques to health related problems of renal and hypertensive disease that include studies of renal mechanisms of blood pressure and volume homeostasis, receptor regulation, vascular physiology, pharmacology and angiogenesis, intracellular signaling, oxidative stress, effects of gender and pregnancy on vascular function, molecular genetics and interactions between vasoactive factors in the kidney. Candidates will have the MD and/or PhD. Physicians will have completed clinical training in either internal medicine or pediatrics and most will undertake clinical subspecialty training in nephrology. The research training program will be for 2 years, during which patient care activities will be strictly limited. Candidates will be selected by the entire faculty based upon stated career goals in research and academic nephrology, interviews, letters of recommendation, and past performance. Progress of candidates will be assessed by the program director and co-director, individual faculty preceptors, review by the training faculty and review of formal presentations and written progress reports. All training will be carried out at Georgetown University Medical Center, in the laboratories of a cohesive and highly collaborative group of training faculty drawn from the Departments of Medicine, Pediatrics, Pharmacology, Physiology, and Oncology. Five of the seven core faculty are the Pi's of an NIH Program Project Grant. They undertake research supported by core facilities. The training and support faculty are drawn from many departments in the newly formed Cardiovascular Kidney Institute. This provides a cohesive and collaborative research environment in which to provide basic science research training for selected trainees. The aim is to train physicians and post doctoral scientists, for a career in academic nephrology and hypertension.

描述（由申请人提供）： 这是针对肾脏病学和高血压领域的博士后培训生的研究培训计划的提案。目标是帮助医生和科学家做好对肾脏和高血压疾病以及正常和异常肾功能或血压调节基础生物学的独立研究的准备。我们强调将尖端基础研究技术应用于肾脏和高血压疾病的健康相关问题，包括血压和容量稳态的肾脏机制、受体调节、血管生理学、药理学和血管生成、细胞内信号传导、氧化应激、性别影响的研究和妊娠对血管功能、分子遗传学以及肾脏血管活性因子之间相互作用的影响。候选人将拥有医学博士和/或博士学位。医生将完成内科或儿科的临床培训，大多数将接受肾脏病学的临床专科培训。研究培训计划为期2年，期间患者护理活动将受到严格限制。候选人将由全体教员根据研究和学术肾病学的既定职业目标、面试、推荐信和过去的表现来选择。候选人的进步将由项目主任和联合主任、个别教师导师进行评估，由培训教师进行审查，并审查正式演示和书面进度报告。所有培训都将在乔治城大学医学中心的实验室中进行，该实验室由来自医学、儿科、药理学、生理学和肿瘤学系的培训教师组成的具有凝聚力和高度协作性的团队组成。七名核心教师中有五名是 NIH 项目资助的 Pi。他们在核心设施的支持下进行研究。培训和支持人员来自新成立的心血管肾脏研究所的许多部门。这提供了一个有凝聚力和协作的研究环境，为选定的学员提供基础科学研究培训。其目的是培训医生和博士后科学家，从事肾脏病学和高血压领域的学术职业。