Mentored research in the intersection of kidney and cardiovascular disease

肾脏和心血管疾病交叉领域的指导研究

• 批准号: 10795588
• 负责人: Nisha Bansal
• 金额: $ 10.97万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-06 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10795588
• 关键词: Academia; Acute Renal Failure with Renal Papillary Necrosis; Address; Administrative Supplement; Alaska; American Indians; Arrhythmia; Asian Americans; Award; Awareness; Cardiovascular Diseases; Chronic Kidney Failure; Clinical; Clinical Trials; Coupled; Development; Diagnosis; Dialysis procedure; Disease; Disparity; Education; Educational Status; Endowment; Ethnic Origin; Family; Fellowship; Foundations; Functional disorder; Funding; Future; Gender; Geography; Grant; Growth; Heart failure; Idaho; Individual; Journals; Kidney Diseases; Kidney Failure; Kidney Transplantation; Leadership; Lesbian Gay Bisexual Transgender Queer; Measures; Medicine; Mentors; Mentorship; Mission; Montana; National Institute of Diabetes and Digestive and Kidney Diseases; Nephrology; Pacific Islander; Patients; Persons; Philosophy; Physicians; Postdoctoral Fellow; Productivity; Publications; Publishing; Race; Research; Research Infrastructure; Research Support; Resources; Scholarship; Science; Scientist; Socioeconomic Status; Source; Students; Talents; Time; Training; Underrepresented Populations; United States National Institutes of Health; Universities; Washington; Woman; Work; Wyoming; career; doctoral student; education research; epidemiology study; health equity; hypertension treatment; interest; next generation; outreach program; patient oriented research; post-doctoral training; professor; programs; racial diversity; racism; risk stratification; rural area; sex; success; training opportunity

ABSTRACT I am a mid-career nephrologist, a newly promoted Professor, the holder of Arthur Stach Endowed Professorship and the Director of Nephrology Clinical and Research Education in the Division of Nephrology at the University of Washington (UW). I have been a NIDDK-funded physician-scientist since the completion of my fellowship in 2010; and have an active patient-oriented research program that focuses on the intersection of kidney and cardiovascular disease. My work encompasses epidemiological studies, mechanistic studies, and clinical trials all focused on the pathophysiology, diagnosis, risk stratification and treatment of hypertension, heart failure and cardiac arrhythmias in patients with chronic kidney disease, acute kidney injury and kidney failure (treated with dialysis or kidney transplant). I am currently the PI of three NIH R01s, the co- Director of the UW Nephrology NIDDK T32, co-I on two NIH U01s and the PI of two NIH administrative supplements. One of the greatest joys and privileges of my career to date has been the opportunity to serve as mentor. My success as a mentor is measured by my mentee’s success. My current and previous grants have provided numerous rich opportunities for training for post-doctoral students, residents and fellows. I have been a mentor for 24 talented individuals since 2010, including 63% women, 50% Asian American persons, 30% persons underrepresented in medicine or science by race, ethnicity, gender identify and family educational status. Of these, 63% of my mentees remain in academia and continue in scholarship or research. The work of these mentees has been productive, yielding >40 first author publications and ten NIH or foundation grants. There is a critical need to increase mentorship for individuals from diverse backgrounds. It is well known that advances in NIDDK-focused diseases are in crisis as fewer physician and scientists choose to pursue research careers. In particular, diverse research teams are needed to address racism and disparities in medicine and science. Mentorship is a critical factor cited by students for inspiring their interest in scientific careers. Locally, the UW, located in Seattle, WA, is unique in its mission to attract trainees from across a five-state region of Washington, Wyoming, Alaska, Montana and Idaho, who are diverse by race (including American Indian and Pacific Islander), ethnicity, sex, gender, geography (many from rural areas), ability, LGBTQ+ and socioeconomic status. Coupled with established outreach programs at UW and the sizable pool of post- doctoral trainees from these diverse backgrounds, there is tremendous opportunity to cultivate the next generation of NIDDK diverse scientists in this region. I am committed to mentoring persons from backgrounds underrepresented in medicine and science to increase the diversity of the future NIDDK biomedical scientific workforce. This award will provide key resources, training and professional development that will enhance my ability to serve as an effective mentor for post-doctoral trainees from diverse backgrounds.

抽象的 我是一名职业肾脏科医生，新晋升的教授，Arthur Stach的持有者 教授职位和肾脏病临床和研究教育主任肾脏科学系 华盛顿大学（UW）。自从完成以来，我一直是NIDDK资助的身体科学家 我在2010年的奖学金；并拥有一个活跃的面向患者的研究计划，该计划的重点是交叉路口 我的工作包括流行病学研究，机理研究， 和临床试验都集中在病理生理学，诊断，风险分层和治疗 慢性肾脏疾病患者，急性肾脏损伤患者的高血压，心力衰竭和心律不齐 和肾衰竭（用透析或肾脏移植治疗）。我目前是三个NIH R01的PI，共同 UW肾脏学主任NIDDK T32，Co-I两个NIH U01和两个NIH行政的PI 补品。迄今为止我职业的最大欢乐和特权之一就是机会 导师。我作为导师的成功是通过我的成功衡量的。 我目前和以前的赠款为博士后提供了许多丰富的机会 学生，居民和研究员。自2010年以来，我一直是24个才华横溢的人的心理，其中包括63％ 妇女，50％的亚裔美国人，有30％的人在种族中的医学或科学人数不足， 种族，性别认同和家庭教育地位。其中，我有63％的Menees留在学术界， 继续从事科学或研究。这些月经的工作富有成效，产生> 40个第一作者 出版物和十个NIH或基金会赠款。 对于潜水员背景的个人来说，迫切需要提高心态。众所周知 以NIDDK为重点的疾病的进步处于危机状态，因为较少的身体和科学家选择从事研究 职业。特别是，需要潜水员研究团队来解决医学的种族主义和差异， 科学。指导是学生激发他们对科学职业兴趣的关键因素。在本地， 位于华盛顿州西雅图市的西澳大学在其任务中独特地吸引了从五个州地区的培训 华盛顿，怀俄明州，阿拉斯加，蒙大拿州和爱达荷州，他们是种族的潜水员（包括美洲印第安人和 太平洋岛民），种族，性别，性别，地理（许多来自粗糙地区），能力，LGBTQ+和 社会经济地位。加上UW的既定外展计划，以及相当大的后库 这些不同背景的博士学员，有很多机会培养下一个 该地区的Niddk潜水员科学家的一代。我致力于从背景的心理人员 医学和科学的代表性不足，无法提高未来的NIDDK生物医学科学的多样性 劳动力。该奖项将提供关键资源，培训和专业发展，以增强我的 能够成为来自潜水员背景的博士后学员的有效心理。