Mentored research in the intersection of kidney and cardiovascular disease

肾脏和心血管疾病交叉领域的指导研究

基本信息

批准号：
10795588
负责人：
Nisha Bansal
金额：
$ 10.97万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-06 至 2028-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10795588
关键词：
Academia Acute Renal Failure with Renal Papillary Necrosis Address Administrative Supplement Alaska American Indians Arrhythmia Asian Americans Award Awareness Cardiovascular Diseases Chronic Kidney Failure Clinical Clinical Trials Coupled Development Diagnosis Dialysis procedure Disease Disparity Education Educational Status Endowment Ethnic Origin Family Fellowship Foundations Functional disorder Funding Future Gender Geography Grant Growth Heart failure Idaho Individual Journals Kidney Diseases Kidney Failure Kidney Transplantation Leadership Lesbian Gay Bisexual Transgender Queer Measures Medicine Mentors Mentorship Mission Montana National Institute of Diabetes and Digestive and Kidney Diseases Nephrology Pacific Islander Patients Persons Philosophy Physicians Postdoctoral Fellow Productivity Publications Publishing Race Research Research Infrastructure Research Support Resources Scholarship Science Scientist Socioeconomic Status Source Students Talents Time Training Underrepresented Populations United States National Institutes of Health Universities Washington Woman Work Wyoming career doctoral student education research epidemiology study health equity hypertension treatment interest next generation outreach program patient oriented research post-doctoral training professor programs racial diversity racism risk stratification rural area sex success training opportunity

项目摘要

ABSTRACT I am a mid-career nephrologist, a newly promoted Professor, the holder of Arthur Stach Endowed Professorship and the Director of Nephrology Clinical and Research Education in the Division of Nephrology at the University of Washington (UW). I have been a NIDDK-funded physician-scientist since the completion of my fellowship in 2010; and have an active patient-oriented research program that focuses on the intersection of kidney and cardiovascular disease. My work encompasses epidemiological studies, mechanistic studies, and clinical trials all focused on the pathophysiology, diagnosis, risk stratification and treatment of hypertension, heart failure and cardiac arrhythmias in patients with chronic kidney disease, acute kidney injury and kidney failure (treated with dialysis or kidney transplant). I am currently the PI of three NIH R01s, the co- Director of the UW Nephrology NIDDK T32, co-I on two NIH U01s and the PI of two NIH administrative supplements. One of the greatest joys and privileges of my career to date has been the opportunity to serve as mentor. My success as a mentor is measured by my mentee’s success. My current and previous grants have provided numerous rich opportunities for training for post-doctoral students, residents and fellows. I have been a mentor for 24 talented individuals since 2010, including 63% women, 50% Asian American persons, 30% persons underrepresented in medicine or science by race, ethnicity, gender identify and family educational status. Of these, 63% of my mentees remain in academia and continue in scholarship or research. The work of these mentees has been productive, yielding >40 first author publications and ten NIH or foundation grants. There is a critical need to increase mentorship for individuals from diverse backgrounds. It is well known that advances in NIDDK-focused diseases are in crisis as fewer physician and scientists choose to pursue research careers. In particular, diverse research teams are needed to address racism and disparities in medicine and science. Mentorship is a critical factor cited by students for inspiring their interest in scientific careers. Locally, the UW, located in Seattle, WA, is unique in its mission to attract trainees from across a five-state region of Washington, Wyoming, Alaska, Montana and Idaho, who are diverse by race (including American Indian and Pacific Islander), ethnicity, sex, gender, geography (many from rural areas), ability, LGBTQ+ and socioeconomic status. Coupled with established outreach programs at UW and the sizable pool of post- doctoral trainees from these diverse backgrounds, there is tremendous opportunity to cultivate the next generation of NIDDK diverse scientists in this region. I am committed to mentoring persons from backgrounds underrepresented in medicine and science to increase the diversity of the future NIDDK biomedical scientific workforce. This award will provide key resources, training and professional development that will enhance my ability to serve as an effective mentor for post-doctoral trainees from diverse backgrounds.

抽象的我是一名职业生涯中期的肾病专家，新晋升的教授，Arthur Stach Endowed 的持有者肾脏病科教授兼肾脏病临床和研究教育主任自从完成学业以来，我一直是 NIDDK 资助的医师科学家。我在 2010 年获得了奖学金；并且有一个积极的以患者为中心的研究项目，重点关注交叉点我的工作包括流行病学研究、机制研究、和临床试验均侧重于病理生理学、诊断、风险分层和治疗慢性肾病、急性肾损伤患者的高血压、心力衰竭和心律失常我目前是三名 NIH R01 的 PI，即联合治疗师。华盛顿大学肾病科 NIDDK T32 主任、两个 NIH U01 的联合研究员和两个 NIH 行政部门的 PI 迄今为止，我职业生涯中最大的乐趣和特权之一就是有机会担任我作为导师的成功是通过我的受训者的成功来衡量的。我当前和之前的资助为博士后培训提供了许多丰富的机会自 2010 年以来，我一直是 24 名才华横溢的人的导师，其中包括 63%。女性、50% 亚裔美国人、30% 因种族原因在医学或科学领域代表性不足的人，其中，63% 的学员仍在学术界和家庭教育状况。这些受训者的工作卓有成效，产生了超过 40 位第一作者。出版物和十项 NIH 或基金会拨款。众所周知，迫切需要加强对来自不同背景的个人的指导。由于越来越少的医生和科学家选择从事研究，以 NIDDK 为重点的疾病的进展陷入危机特别是需要多元化的研究团队来解决医学和职业方面的种族主义和差异。导师制是激发学生对当地科学职业兴趣的一个关键因素。华盛顿大学位于华盛顿州西雅图，其独特的使命是吸引来自美国五个州地区的学员华盛顿州、怀俄明州、阿拉斯加、蒙大拿州和爱达荷州，这些州的种族多种多样（包括美洲印第安人和太平洋岛民）、种族、性别、性别、地理位置（许多来自农村地区）、能力、LGBTQ+ 和再加上威斯康星大学既定的外展计划和大量的失业人员。来自这些背景的博士生，有巨大的多样化机会来培养下一个我致力于指导该地区的一代 NIDDK 多元化科学家。医学和科学领域代表性不足，以增加未来 NIDDK 生物医学科学的多样性该奖项将提供关键资源、培训和专业发展，以增强我的员工队伍。能够为来自不同背景的博士后学员提供有效的导师。