Regulation of microvascular function by ROS

ROS对微血管功能的调节

• 批准号: 8148026
• 负责人: CHRISTOPHER S WILCOX
• 金额: $ 47.4万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8148026
• 关键词: Accounting; Agonist; Angiotensin II; Blood Vessels; Buffers; Complication; Contracts; Cuprozinc Superoxide Dismutase; Development; Endothelin-1; Endothelium; Enzyme Activators; Equilibrium; Excretory function; Gene Expression; Gene Silencing; Generations; Homeostasis; Hydrogen Peroxide; Hypertension; Infusion procedures; Injection of therapeutic agent; Intake; Intravenous; Kidney; Knock-out; Knockout Mice; Lead; Lipid Peroxidation; Mesentery; Metabolism; Modeling; Molecular; Multienzyme Complexes; Mus; NADP; NADPH Oxidase; Nitric Oxide; Nox enzyme; Oryctolagus cuniculus; Oxidation-Reduction; Oxidative Stress; Pharmaceutical Preparations; Play; Process; Prostaglandin-Endoperoxide Synthase; Prostaglandins; Protein Isoforms; Proteins; RNA Interference; Rattus; Reactive Oxygen Species; Regulation; Relaxation; Research Design; Resistance; Rho-associated kinase; Role; Small Interfering RNA; Smooth Muscle Myocytes; Sodium Chloride; Source; Superoxide Dismutase; Superoxides; Testing; Thromboxane Receptor; Thromboxanes; Time; Up-Regulation; Vascular resistance; Vasoconstrictor Agents; arteriole; base; cyclooxygenase 1; design; feeding; hemodynamics; human CYBA protein; in vivo; inhibitor/antagonist; kidney vascular structure; mouse model; prevent; receptor; research study; response; rho