Confocal Microscope

共焦显微镜

• 批准号: 6878277
• 负责人: TADMIRI Rangachar VENKATESH
• 金额: $ 19.97万
• 依托单位: CITY COLLEGE OF NEW YORK
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-04-01 至 2006-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6878277
• 关键词: biomedical equipment purchase; cell biology; confocal scanning microscopy; developmental neurobiology; hematopoiesis; learning; molecular /cellular imaging; neurogenesis

DESCRIPTION (provided by applicant): This proposal requests funds for a confocal microscope to be used as shared imaging instrument by the faculty in the department of biology at the City College of New York. The confocal microscope will facilitate the research activities of eight NIH-funded investigators some of whom already use confocal microscopy in their research, and will enable others to initiate a new dimension to their ongoing research activities. At the present time there is no confocal microscope available in any of the departments of the Division of science at City College. The current users of the confocal microscopy are using for-fee facilities at other research institutions in New York and Boston. A total of nine principal investigators and over 40 research personnel including postdoctoral fellows, graduate students, undergraduates, and research assistants will use the requested microscope on a daily basis. The research projects of the users cover a diverse variety of confocal applications that include: cellular basis of song learning in birds, neurotransmitter function in nematodes, neuronal development in Drosophila and higher vertebrates, studies on Foraminifera, thymic nurse cell function and Drosophila hematopoiesis and immune response. The use of a confocal microscope is critical for these studies. Funds are requested for a Nikon C1 confocal microscope. This microscope has high quality optics, resolution and excellent image quality and is versatile and compatible to most imaging software. In addition, the low cost of the microscope and quality of service as compared to other manufacturers were important points of concern. The confocal microscope is a key essential instrument and relatively standard in most departments. Acquisition of the confocal microscope will greatly enhance the quality and the productivity of the NIH funded investigators at City College.

描述（由申请人提供）：该提案要求资助一台共焦显微镜，作为纽约城市学院生物系教师共享的成像仪器。共焦显微镜将促进 NIH 资助的八名研究人员的研究活动，其中一些研究人员已经在他们的研究中使用共焦显微镜，并使其他人能够为他们正在进行的研究活动开启一个新的维度。目前，城市学院科学部的任何部门都没有共焦显微镜。共焦显微镜的当前用户正在使用纽约和波士顿其他研究机构的免费设施。共有 9 名主要研究人员和 40 多名研究人员（包括博士后、研究生、本科生和研究助理）每天使用所需的显微镜。用户的研究项目涵盖多种共聚焦应用，包括：鸟类鸣叫学习的细胞基础、线虫的神经递质功能、果蝇和高等脊椎动物的神经元发育、有孔虫研究、胸腺护理细胞功能以及果蝇造血和免疫回复。共焦显微镜的使用对于这些研究至关重要。需要资金购买尼康 C1 共焦显微镜。该显微镜具有高质量的光学器件、分辨率和出色的图像质量，用途广泛且与大多数成像软件兼容。此外，与其他制造商相比，显微镜的低成本和服务质量也是重要的关注点。共焦显微镜是重要的必备仪器，在大多数科室中都是相对标准的。购买共焦显微镜将大大提高 NIH 资助的城市学院研究人员的质量和生产力。