Novel Photon Counting Clinical CT Detectors

新型光子计数临床 CT 探测器

基本信息

批准号：
7482068
负责人：
WILLIAM C BARBER
金额：
$ 14.2万
依托单位：
DXRAY, INC.
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-04-01 至 2008-09-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7482068
关键词：
Address Algorithms Anodes Area Binding Calcified Calcium Ceramics Clinical Code Collaborations Compatible Computer software Computers Consumption Contrast Media Count Coupled Custom DAQ Data Detection Development Diagnostic radiologic examination Dimensions Discrimination Dose Electronics Encapsulated Fibrosis Floods Floor Gadolinium Goals Grant Histocompatibility Testing Image Imaging Phantoms Imaging Techniques Imaging technology Individual Iodine Lateral Literature Mammography Manufacturer Name Marketing Measures Mechanics Methods Mind Modeling Morphologic artifacts Motor Noise Numbers Object Attachment Operating System Output Patients Performance Phase Photons Physiologic pulse Polychlorinated Biphenyls Power Sources Printing Property Pulse taking Radiation Range Rate Reading Records Research Resolution Risk Roentgen Rays Running Sampling Scanning Semiconductors Side Signal Transduction Simulate Slice Small Business Funding Mechanisms Small Business Innovation Research Grant Solid Source Speed Staging Standards of Weights and Measures Surface System Technology Temperature Testing Thick Tissues Tube United States Universities Weight Width X-Ray Computed Tomography base bone cadmium telluride cold temperature commercialization cost data acquisition density design detector feeding improved irradiation new technology next generation novel physical property programs prototype reconstruction response simulation size soft tissue statistics tumor voltage

项目摘要

DESCRIPTION (provided by applicant): Photon counting detectors with energy binning can improve CT performance by counting and binning each x-ray detected. Photon counting x-ray detectors applied to mammography and radiography have shown a dose reduction of 40% to 400% while maintaining sufficient contrast for these applications. For use in CT these detectors are limited, due to an upper bound in terms of their maximum count rate, and advances in maximum count rate capabilities is needed. In order to overcome count rate limitations, new technological developments in reducing the size of application specific integrated circuits (ASICs) has been applied to reading out semiconductor detectors. These advancements, along with improvements to the cost and reliability of the compound semiconductor cadmium telluride (CdTe), allow us to develop a photon counting detector and read-out technology for CT. Therefore the overall goal of this Fast Track Phase I/Phase II proposal is to develop a photon counting CT detector with energy binning and read-out that is capable of producing energy resolved CT scan which can deliver less radiation dose and differentiate between tissue types.

描述（由申请人提供）：具有能量箱的光子计数检测器可以通过计数和汇总每个检测到的X射线来改善CT性能。用于乳房X线摄影和X线摄影的光子计数X射线检测器显示，剂量降低了40％至400％，同时对这些应用保持了足够的对比度。为了在CT中使用这些检测器，由于其最大计数率的上限是有限的，因此需要最大计数能力的进步。为了克服计数率限制，在减少应用特定集成电路（ASIC）规模的新技术发展已应用于读取半导体检测器。这些进步以及改善了化合物半导体池塘尿酸钙（CDTE）的成本和可靠性，使我们能够开发用于CT的光子计数检测器和读取技术。因此，此快速轨道I/II期建议的总体目标是开发具有能量箱和读取的光子计数CT检测器，该检测器能够产生能量解析的CT扫描，从而可以提供较少的辐射剂量并区分组织类型。