A High-Flow Personal Sampler for Inhalable Aerosol

用于吸入气溶胶的高流量个人采样器

基本信息

批准号：
7491648
负责人：
John Volckens
金额：
$ 21.39万
依托单位：
COLORADO STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-08-01 至 2010-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7491648
关键词：
Flow Personal Sampler Inhalable Aerosol

项目摘要

DESCRIPTION (provided by applicant): While occupational respiratory diseases inflict a severe toll on our national workforce, existing exposure assessment methods for many respiratory hazards lack sufficient detection sensitivity, preventing the practicing industrial hygienist from determining whether a hazard even exists. The goal of this research is to design a high flow sampling device engineered to assess inhalable aerosol hazards in the workplace in a physiologically relevant fashion. This device will extend overall method detection limits by considerably increasing sampler flowrate. The design will be inexpensive and readily-integrated into the commonly used 37-mm filter cassette. Because of its low cost, accuracy, ease-of-use, and adaptability, this device will have widespread application, especially in developing countries where exposure assessment resources and budgets are limited. Such widespread use was a major design goal for this technology, as increased use of an accurate exposure assessment technology will ultimately result in increased protection of worker health on a national and global scale. There are 3 specific aims for this project. First, to design an inexpensive, modular sampling head that (a) interfaces with a standard 37-mm cassette, (b) operates at a high rate of airflow, 10 Lpm, and (c) meets the criteria for inhalable sampling set by the American Conference of Governmental Industrial Hygienists/International Standards Organization. This high-flow design will proceed from a wide body of research on existing low-flow inhalable devices. Second, to evaluate sampler performance using computational fluid dynamic modeling and to refine the prototype design based on results from these tests. Third, to validate the refined design through laboratory tests in a wind tunnel and field tests in actual occupational environments.

描述（由申请人提供）：虽然职业呼吸道疾病对我们的国家劳动力造成了严重损失，但现有的许多呼吸危害的暴露评估方法缺乏可可生的检测敏感性，从而阻止了实践的工业卫生卫生人士确定危害是否存在。这项研究的目的是设计一种高流动采样设备，以生理相关的方式评估工作场所中可吸入的气溶胶危害。该设备将通过大大增加采样器流量来扩展总体方法检测极限。该设计将是便宜的，并且很容易整合到常用的37毫米滤镜中。由于其成本低，准确性，易用性和适应性，该设备将具有广泛的应用，尤其是在曝光评估资源和预算有限的发展中国家。这种技术的广泛使用是这项技术的主要设计目标，因为对准确的曝光评估技术的增加最终将导致在国家和全球规模上增加对工人健康的保护。该项目有3个具体目标。首先，要设计一个廉价的模块化抽样头，（a）与标准的37毫米盒接口，（b）以高气流速度，10 lpm的速度运行，并且（c）符合美国政府政府工业卫生主义者会议设定的可吸入采样标准。这种高流量设计将从现有的低流量吸入设备的大量研究中进行。其次，使用计算流体动态建模评估采样器性能，并根据这些测试的结果来完善原型设计。第三，通过在实际职业环境中的风洞和现场测试中的实验室测试来验证精致的设计。