TRANSGENIC MOUSE CORE

转基因小鼠核心

• 批准号: 7381234
• 负责人: MICHAEL J KERN
• 金额: $ 26万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381234
• 关键词: gene targeting; genetically modified animals; genotype; laboratory mouse; microinjections

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall responsibilities of the Transgenic Mouse Core fall into the following four categories: a)Generation of mice-transgenic mice will be generated by both pronuclear microinjection and homologous recombination in ES cells as needed for the five initial investigators and any future investigators recruited. b)Mentoring- the initial and future project leaders will be mentored in the utilization of transgenic and gene targeted technologies. c)Experimentation- all experiments that generate and/or use transgenic/gene targeted mice will be facilitated from concept to completion. d)Utilization of mice- all genetically modified mice will be maintained in the core to facilitate and consolidate breeding, genotyping, and recordkeeping of

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中出现。列出的机构是中心的机构，不一定是研究者的机构。转基因小鼠核心的总体职责分为以下四类： a) 根据五名初始研究人员和任何未来招募的研究人员的需要，将通过原核显微注射和 ES 细胞同源重组产生小鼠转基因小鼠。 b) 指导——最初和未来的项目负责人将在转基因和基因靶向技术的利用方面得到指导。 c) 实验——所有产生和/或使用转基因/基因靶向小鼠的实验从概念到完成都将得到促进。 d) 小鼠的利用——所有转基因小鼠都将保留在核心中，以促进和巩固小鼠的育种、基因分型和记录保存