METABOLIC EFFECTS OF GROWTH HORMONE UPON BODY COMPOSITION IN TODDLERS WITH PWS

生长激素对 PWS 幼儿身体成分的代谢影响

• 批准号: 7375485
• 负责人: AARON L CARREL
• 金额: $ 0.22万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7375485
• 关键词: METABOLIC; EFFECTS; GROWTH; HORMONE; UPON

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Prader-Willi syndrome (PWS) is a rare genetic disorder associated with obesity. Early in life, children with PWS demonstrate poor weight gain and low muscle tone. This study evaluates the effect of growth hormone (GH) upon these conditions. This randomized controlled study will compare children with PWS treated with GH compared to control PWS children. Outcomes will include measuring body fat, muscle mass, energy expenditure, hormonal levels an

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。 Prader-Willi综合征（PWS）是与肥胖有关的罕见遗传疾病。在生命的早期，患有PWS的儿童体重增加较差，肌肉张力低下。这项研究评估了生长激素（GH）对这些条件的影响。这项随机对照研究将比较用GH处理的PW与对照PWS儿童相比。结果将包括测量体内脂肪，肌肉质量，能量消耗，荷尔蒙水平