EFFECT OF EXERCISE & DIET ON ENERGY EXPENDITURE & BODY COMPOSITION IN

运动的效果

• 批准号: 6265757
• 负责人: AARON L CARREL
• 金额: $ 3.35万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6265757
• 关键词: adolescence (12-20); bioenergetics; body composition; child (0-11); clinical research; diet; exercise; human subject; human therapy evaluation; nutrition related tag; obesity

Obesity is increasing significantly in affluent societies, this trend includes children and adolescents. Weight gain results from caloric intake exceeding caloric (energy) expenditure. The increase in prevalence of obesity represents a population shift towards positive energy balance. Dietary intake and physical activity represent the behavioral, and therefore modifiable aspects of this balance equation, unlike energy expenditure. It has been shown that reduced energy expenditure may constitute a risk factor for obesity for infants of overweight mothers, Pima Indian adults, and children with Prader-Willi syndrome, although this is less clear in other populations. Recent studies show that physical exercise has a pronounced protective effect against weight gain in adults. These studies have not been performed in otherwise healthy obese children and adolescents. This study will assess the effect of a low-fat (<30% total calories) diet and a moderate intensity exercise program in healthy obese children and adolescents upon energy expenditure and body composition compared to control patients: obese children who receive "standard" advice (without formal follow-up) for weight management. These determinations will be accomplished using indirect calorimetry, doubly labelled water (DLW), and DEXA (dual energy x-ray absorptiometry) analysis. The long-term goals of this project are to improve the understanding and recommendations for the prevention and treatment of obesity in children.

在富裕的社会中，肥胖症正在显着增加，这种趋势包括儿童和青少年。 体重增加来自热量超过热量（能量）支出的结果。 肥胖症患病率的增加代表了人口向正能量平衡的转变。 与能量消耗不同，饮食摄入和体育锻炼代表了该平衡方程式的行为，因此可以改变该平衡方程式。 已经表明，减少的能量消耗可能构成超重母亲，皮马印度成年人和Prader-Willi综合征儿童的肥胖症的危险因素，尽管这在其他人群中尚不清楚。 最近的研究表明，体育锻炼具有明显的保护作用，以抵抗成人体重的增长。 这些研究尚未在其他健康的肥胖儿童和青少年中进行。这项研究将评估健康肥胖儿童和青少年中低脂（<30％的总卡路里）饮食和中等强度运动计划对能量消耗和身体成分的影响：与对照患者相比：接受体重管理的“标准”建议（无正式随访）的肥胖儿童。 这些确定将使用间接量热法，双重标记的水（DLW）和DEXA（双能X射线吸收计）分析来完成。 该项目的长期目标是提高预防和治疗儿童肥胖症的理解和建议。