PREVENTION OF CHRONIC ASTHMA: AGE 7 FOLLOW-UP

预防慢性哮喘：7 岁随访

• 批准号: 7377739
• 负责人: Mary D. Klinnert
• 金额: $ 1.36万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7377739
• 关键词: PREVENTION; CHRONIC; ASTHMA; AGE; FOLLOW

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study investigates the efficacy of an early environmental with children at risk for asthma. In addition this study also investigates the natural history of asthma and the psychosocial and environmental issues surrounding childhood asthma in a low-income population. This proposal follows the progress of the subjects previously enrolled in the Childhood Asthma Prevention Study (CAPS). The subjects were enrolled because they had 3 or more physician-documented episodes of wheezing prior to the age of 2 and were from low-income families. Both of these factors put them at risk for childhood asthma. In the previous phase of the CAPS study, the families were randomized into two different intervention groups. Those families in the treatment condition had a nurse home-visitor work with them for a year on an asthma management protocol. The families in the information control group received written information about asthma management only. At four years of age, the children were assessed for asthma status. This proposal follows these children until the age of 7 years when asthma status will again be assessed to test the efficacy of the intervention. The families will be contacted to begin this follow-up when the children are 6 years old. The follow-up will then continue for a year until the children are 7 when they come into National Jewish for a medical evaluation.

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中出现。列出的机构是中心的机构，不一定是研究者的机构。这项研究调查了早期环境对有哮喘风险的儿童的功效。此外，这项研究还调查了低收入人群中哮喘的自然史以及围绕儿童哮喘的社会心理和环境问题。该提案遵循先前参加儿童哮喘预防研究 (CAPS) 的受试者的进展。这些受试者被纳入研究是因为他们在 2 岁之前有过 3 次或以上医生记录的喘息发作，并且来自低收入家庭。这两个因素都使他们面临儿童哮喘的风险。在 CAPS 研究的前一阶段，这些家庭被随机分为两个不同的干预组。这些接受治疗的家庭有一名护士家访人员与他们一起进行为期一年的哮喘管理方案。信息对照组的家庭仅收到有关哮喘管理的书面信息。四岁时，对孩子们进行了哮喘状况评估。这项建议将持续到这些儿童 7 岁为止，届时将再次评估哮喘状况，以测试干预措施的效果。当孩子 6 岁时，我们将联系家庭开始这项后续行动。后续行动将持续一年，直到孩子们7岁时进入国家犹太医院接受医学评估。