The Influence of Heart Failure Self-Care Behavior on Cardiac Performance

心力衰竭自我护理行为对心脏功能的影响

• 批准号: 7274456
• 负责人: Christopher Sean Lee
• 金额: $ 2.96万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2010-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7274456
• 关键词: Abdomen; Acceleration; Adherence; Affect; American; Atrial Natriuretic Factor; Behavior; Blood; Blood Plasma Volume; Blood Volume; Cardiac; Chest; Clinical; Complex; Cross-Sectional Studies; Decision Making; Development; Endocrine; Force of Gravity; Fostering; Functional disorder; Future; Head-Down Tilt; Health; Heart; Heart Atrium; Heart failure; Hormonal; Hormones; Hour; Intervention; Invasive; Knowledge; Lead; Left; Leg; Liquid substance; Measurable; Measurement; Measures; Medical; Monitor; Morbidity - disease rate; Outcome; Outcome Study; Patients; Performance; Persons; Physiological; Play; Positioning Attribute; Procedures; Process; Purpose; Quality of life; Rate; Relative (related person); Research Personnel; Rest; Role playing therapy; Score; Self Care; Sodium; Sodium-Restricted Diet; Stress; Stretching; Stroke Volume; Symptoms; Syndrome; Techniques; Technology; Time; Translations; Urine; Work; base; cardiography; day; design; disability; experience; heart function; hemodynamics; hospital readmission; improved; indexing; innovation; insight; research study; response; theories

DESCRIPTION (provided by applicant): Heart failure (HF), a syndrome that affects more than five million Americans, is associated with disability, increased morbidity, and decreased quality-of-life. Self-care may be one way of controlling fluid retention and endocrine responses to HF that impair cardiac performance and lead to poor patient outcomes. Although self-care is hypothesized to influence cardiac performance, the scientific basis of this claim has not yet been established. We need further evidence that HF patient's day-to-day self-care practices can influence cardiac performance in order to impress on patients the important role that they play in maintaining optimal cardiac performance and in increasing the quality and years of their health. We intend to use bioimpedance cardiography technology and hormone measurement, along with a strategic procedure of head-down tilt to passively and non-invasively challenge the heart's performance to gain insight into this relationship. A cross-sectional study is proposed to examine the relationship between HF self-care measured using subjective and objective measures and the objective measurement of cardiac performance in response to fifteen minutes of a 15¿ head-down tilt positional challenge. The specific aims of this study are to: 1) describe the relationship between HF self-care and baseline cardiac performance, by measuring A) self-care with the Self-Care of Heart Failure Index, the Medical Outcomes Study Specific Adherence Scale, and 24-hour urine sodium levels to assess adherence to a low sodium diet, and B) cardiac performance with blood levels of atrial natriuretic peptide, as an index of atrial distension, and cardiac hemodynamics with bioimpedence cardiography, including thoracic fluid volume index, stroke volume index, and acceleration index, and 2) describe the relationship between HF self-care and dynamic cardiac performance in response to a fifteen minute, 15¿ head-down tilt positional challenge. Measures of HF self-care will be compared to the relative change in measures of cardiac performance in response to body positioning. This research study examines the self-care behaviors of persons with heart failure and how their heart functions at rest and when stressed. This study will help determine if the day-to-day self-care behaviors of heart failure patients can influence how the heart functions.

描述（由适用提供）：一种影响超过500万美国人的综合征心力衰竭（HF），与残疾，发病率增加和生活质量增加有关。自我护理可能是控制液体保留率和对HF的内分泌反应的一种方法，而HF会损害心脏表现并导致患者的结果不佳。尽管假设自我保健会影响心脏表现，但尚未确定这种主张的科学基础。我们需要进一步的证据表明，HF患者的日常自我护理实践可以影响心脏表现，以便给患者打动他们在保持最佳心脏性能以及提高健康质量和健康年份中所起的重要作用。我们打算使用生物阻抗的心脏摄影技术和马酮测量，以及一个战略性的倾斜倾斜程序，以被动和非侵入性地挑战心脏的表现，以深入了解这种关系。提出了一项横断面研究，以检查使用主观和客观测量测量的HF自我保健与心脏性能的客观测量，以响应15届倾斜位置挑战的15分钟。 The specific aims of this study are to: 1) describe the relationship between HF self-care and baseline cardiac performance, by measuring A) self-care with the Self-Care of Heart Failure Index, the Medical Outcomes Study Specific Adherence Scale, and 24-hour urine sodium levels to assess adherence to a low sodium diet, and B) cardiac performance with blood levels of atrial natriuretic peptide, as an index of atrial distension, and具有生物阻抗心脏摄影的心脏血流动力学，包括胸腔流体体积指数，中风体积指数和加速度指数，以及2）描述HF自我护理与动态心脏表现之间的关系，以响应15次15届倾斜的倾斜位置挑战。 HF自我护理的测量将与心脏性能的相对变化进行比较，以响应身体定位。这项研究研究了心力衰竭患者的自我保健行为，以及他们的心脏在静止和压力时的功能。这项研究将有助于确定心力衰竭患者的日常自我保健行为是否会影响心脏的功能。