Ovarian Cancer: Prevention and Its Recurrence

卵巢癌：预防及其复发

• 批准号: 6941660
• 负责人: FRANCESMARY MODUGNO
• 金额: $ 1.3万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6941660
• 关键词: cancer prevention; carcinogenesis; meeting /conference /symposium; neoplasm /cancer relapse /recurrence; ovary neoplasms

Following up on our very successful symosium on hormones and ovarian cancer prevention, we propose a series of symposia on prevention. The goal of this symposia series is to understand the genetic and biologic mechanisms involved in ovarian cancer and how these mechanisms can be exploited to devise innovative strategies for the prevention and detection of the disease and its recurrence. It will further address the impact of these modalities on the lives of women and their families. With advances in molecular biology and the emergence of new technologies (e.g., proteomics, genomics), we are gathering remarkable knowledge about the genetic and biologic basis of carcinogenesis. By directly facilitating our understanding of the disease process, this knowledge and technology is suggesting fruitful avenues of primary, secondary and tertiary. This series will bring together leaders in prevention, detection and treatment research in order to exchange their expertise, identify research avenues and form collaborations. The symposia series will be held every other year at the University of Pittsburgh Cancer Institute Herberman Conference Center. The general theme for the series is molecular targets and prevention; each symposium will have a specific theme: immune system, 2005; cell cycle 2006; pharmacogenetics, 2007; hormones 2008; and model systems 2009. The intended audience is basic, clinical and translational researchers in the areas of epidemiology, molecular biology, genetics, cell biology, endocrinology, pathology, gynecologic oncology, and high-throughput technologies, as well as public health researchers and consumer advocates. The specific goals of the workshop include: 1. to further understand the molecular, biologic and genetic mechanisms involved in ovarian cancer that can be targets for prevention; 2. to become familiar with emerging chemoprevention agents and early detection approaches aimed at molecular targets; 3. to learn about new highthroughput technologies; 4. to identify new areas of research based on the molecular mechanisms of the disease;All sessions include 2-3 scientific presentation followed by an open discussion by a leader in the field. A poster session will allow for participation by junior scientists and foster greater exchange of ideas. To date, there have been no other conferences specifically focused on the intersection of ovarian cancer, molecular targets and prevention (other than our 2002 symposium). This series represents a unique opportunity to bring together scientist, policy researchers and consumer advocates to advance the frontier of ovarian cancer research and public health.

继我们关于激素和卵巢癌预防的非常成功的研讨会之后，我们提议举办一系列预防研讨会。该研讨会系列的目标是了解卵巢癌涉及的遗传和生物学机制，以及如何利用这些机制来制定预防和检测该疾病及其复发的创新策略。它将进一步解决这些方式对妇女及其家庭生活的影响。随着分子生物学的进步和新技术（例如蛋白质组学、基因组学）的出现，我们正在收集有关致癌的遗传和生物学基础的丰富知识。通过直接促进我们对疾病过程的理解，这些知识和技术为初级、次级和 第三。该系列将汇集预防、检测和治疗研究领域的领导者，以交流他们的专业知识、确定研究途径并形成合作。该研讨会系列将每隔一年在匹兹堡大学癌症研究所赫伯曼会议中心举行一次。该系列的总主题是分子目标和预防；每次研讨会都有一个特定的主题：免疫系统，2005；细胞周期2006；药物遗传学，2007；荷尔蒙2008；和模型系统 2009。目标受众是流行病学、分子生物学、遗传学、细胞生物学、内分泌学、病理学、妇科肿瘤学和高通量技术领域的基础、临床和转化研究人员，以及公共卫生研究人员和消费者倡导者。具体的 研讨会的目标包括： 1. 进一步了解卵巢癌的分子、生物学和遗传机制，作为预防的目标； 2. 熟悉新兴的化学预防药物和针对分子靶点的早期检测方法； 3.了解新的高通量技术； 4. 根据疾病的分子机制确定新的研究领域；所有会议均包括 2-3 个科学演讲，随后由该领域的领导者进行公开讨论。海报会议将允许初级科学家参与并促进更多的思想交流。迄今为止，还没有其他会议专门关注卵巢癌的交叉点， 分子目标和预防（除了我们 2002 年的研讨会）。该系列提供了一个独特的机会，将科学家、政策研究人员和消费者倡导者聚集在一起，推动卵巢癌研究和公共卫生的前沿发展。