Conference Proposal: FASEB Nucleic Acid Enzymes

会议提案：FASEB 核酸酶

• 批准号: 7114548
• 负责人: BARRY L. STODDARD
• 金额: $ 0.3万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-12 至 2007-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7114548
• 关键词: DNA repair; enzymes; meeting /conference /symposium; nucleic acids; polymerization; travel

DESCRIPTION (provided by applicant): The meeting entitled "Nucleic Acid Enzymes" will focus on the structures, mechanisms, biological roles, and medical relevance of enzymes that are composed of, and/or act on DNA and RNA. The meeting attracts a broad cross-disciplinary group of scientists with expertise in structural biology, biochemistry, and cell biology. This meeting will be the 6th sponsored by the Federation of American Societies of Experimental Biology (FASEB) in this area; the most recent was in 2004. The meeting provides a unique forum for the discussion of enzymes that are composed of, or act on nucleic acids, the central role of DNA and RNA enzymology in biotechnology, and the growing list of metabolic disorders and diseases in which nucleic acid enzymes are implicated. By bringing together structural biologists, biochemists, cell biologists and clinicians to discuss common interests, new insights and interdisciplinary collaboration are fostered. The Scientific Program will consist of eight sessions of oral presentations by distinguished invited speakers in the following subject areas: (1) Polymerization and Fidelity; (2) Nucleases; (3) Nucleic acid processing and modification; (4) DNA repair; (5 & 6) RNA catalysts and splicing I and II; (7) Recombination and transposition; and (8) peptide bond formation by RNA. The organizers have recruited leading investigators to serve as discussion leaders for these sessions. The Program will also include daily poster sessions, from which outstanding posters from graduate students and post-doc attendees will be selected for short oral presentations. To foster a 'fresh' approach and significant intellectual turnover and renewal, the majority of invited speakers are new to the meeting, and a significant percentage are junior faculty and women in science, as described in the proposal. The FASEB 2006 meeting aims to highlight several emerging themes in nucleic acids enzymology: the application of single-molecule methods to study of nucleic acid enzymes, the interplay between peptide synthesis and RNA processing, the parallels between enzymes involved in DNA metabolism and those of the RNA world, and the burgeoning impact of nucleic acid enzymes on biotechnology and medicine. The intimate format of the conference is designed to promote free exchange of information and ideas among researchers who work on diverse aspects of RNA and DNA enzymes - thereby expediting research in both fields.

描述（由申请人提供）：题为“核酸酶”的会议将重点讨论由 DNA 和 RNA 组成和/或作用于 DNA 和 RNA 的酶的结构、机制、生物学作用和医学相关性。 这次会议吸引了广泛的跨学科科学家小组，他们在结构生物学、生物化学和细胞生物学方面拥有专业知识。 本次会议将是美国实验生物学会联合会（FASEB）在该领域主办的第六次会议；最近一次是在 2004 年。这次会议提供了一个独特的论坛，讨论由核酸组成或作用于核酸的酶、DNA 和 RNA 酶学在生物技术中的核心作用，以及生物技术中日益增多的代谢紊乱和疾病。涉及哪些核酸酶。 通过将结构生物学家、生物化学家、细胞生物学家和临床医生聚集在一起讨论共同的兴趣，可以培养新的见解和跨学科合作。 科学计划将包括八场由特邀演讲者在以下主题领域进行的口头报告： (1) 聚合和保真度； (2) 核酸酶； (3)核酸加工和修饰； (4)DNA修复； (5 & 6) RNA催化剂和剪接I和II； (7) 重组和转座； (8)RNA形成肽键。 组织者招募了主要研究人员作为这些会议的讨论领导者。 该计划还将包括每日海报会议，将从研究生和博士后参加者中选出优秀的海报进行简短的口头演讲。 为了促进“新鲜”方法和显着的知识流动和更新，大多数受邀演讲者都是会议的新成员，其中很大一部分是科学领域的初级教师和女性，正如提案中所述。 FASEB 2006 会议旨在强调核酸酶学中的几个新兴主题：应用单分子方法研究核酸酶、肽合成和 RNA 加工之间的相互作用、参与 DNA 代谢的酶与 DNA 代谢中的酶之间的相似性。 RNA 世界，以及核酸酶对生物技术和医学的新兴影响。会议的亲密形式旨在促进研究 RNA 和 DNA 酶各个方面的研究人员之间自由交流信息和想法，从而加快这两个领域的研究。