Conference--Nucleic Acid Enzymes

会议--核酸酶

• 批准号: 6809005
• 负责人: Robert Landick
• 金额: $ 0.2万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-15 至 2005-07-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6809005
• 关键词: DNA directed RNA polymerase; RNA directed DNA polymerase; enzyme activity; enzymes; exodeoxyribonuclease; meeting /conference /symposium; nucleic acids; nucleoproteins; restriction endonucleases; travel

DESCRIPTION (provided by applicant): The meeting entitled "NUCLEIC ACID ENZYMES: STRUCTURES, MECHANISMS AND NOVEL APPLICATIONS" will focus on the structure, mechanisms, biological roles, and medical relevance of enzymes that act on DNA and RNA. The meeting will attract a broad cross-disciplinary group of scientists with expertise in structural biology, biochemistry, cell biology. This meeting will be the fifth sponsored by the Federation of American Societies of Experimental Biology (FASEB) in the areas of nucleic and enzymologist; the most recent was in 2002. The meeting provides a unique form for the explosion of information on enzymes that act on nucleic acids, the central role of DNA and RNA enzymologist in biotechnology, and the growing list of metabolic disorders and diseased in which nucleic acid enzymes are implicated. By bringing together structural biologists, biochemists, cell biologists and clinicians to discuss common interests, new insights and interdisciplinary collaboration will be fostered. The Scientific Program will consist of eight sessions of oral presentations by distinguished invited speakers in the following subject areas: (1) Transesterification enzymes; (2) Catalysis of phosphoryl transfer by proteins and RNA; (3) Transcription and RNA polymerases; (4) Histone modifications and chromatin remodeling; (5) Enzymology of DNA replication; 6) Single-molecule studies; (7) RNA processing; and (8) Recognition and processing of DNA damage. The organizers have recruited leading investigators to serve as discussion leaders for these sessions. The Program will also include daily poster sessions. All attendees will be encouraged to present posters on their research. To encourage career development of junior scientists, six outstanding posters from the ranks of graduate students and post-doc attendees will be selected for short oral presentations. The FASEB 2004 meeting aims to highlight several emerging themes in nucleic acids Enzymology; the rapidly expanding application of single-molecule methods to study of nucleic acid enzymes, the interplay between chromatin structure and DNA metabolism, the parallels between enzymes involved in DNA metabolism and those of the RNA world, and the burgeoning impact of nucleic acid enzymes on biotechnology and medicine. The intimate format of the conference is designed to promote free exchange of information and ideas among researchers who work on diverse aspects of the RNA and DNA enzymes - thereby expediting research in both fields.

描述（由申请人提供）：题为“核酸酶：结构、机制和新颖应用”的会议将重点讨论作用于 DNA 和 RNA 的酶的结构、机制、生物学作用和医学相关性。 此次会议将吸引具有结构生物学、生物化学、细胞生物学专业知识的广泛跨学科科学家小组。 本次会议将是美国实验生物学会联合会（FASEB）在核酸和酶学家领域主办的第五次会议；最近一次是在 2002 年。这次会议提供了一种独特的形式，展示了有关作用于核酸的酶的信息爆炸式增长、DNA 和 RNA 酶学家在生物技术中的核心作用，以及越来越多的由核酸引起的代谢紊乱和疾病。酶都有涉及。 通过将结构生物学家、生物化学家、细胞生物学家和临床医生聚集在一起讨论共同的兴趣，将促进新的见解和跨学科合作。 该科学计划将包括八场由特邀演讲者在以下主题领域进行的口头报告： (1) 酯交换酶； (2) 蛋白质和RNA催化磷酰基转移； (3) 转录和RNA聚合酶； (4)组蛋白修饰和染色质重塑； (5) DNA复制的酶学； 6）单分子研究； (7)RNA加工； (8)DNA损伤的识别和处理。 组织者招募了主要研究人员作为这些会议的讨论领导者。 该计划还将包括每日海报会议。 我们鼓励所有与会者展示他们的研究海报。 为了鼓励青年科学家的职业发展，将从研究生和博士后队伍中选出六名优秀海报进行简短的口头报告。 FASEB 2004 会议旨在强调核酸酶学中的几个新兴主题；单分子方法在核酸酶研究中的迅速扩展应用、染色质结构与 DNA 代谢之间的相互作用、DNA 代谢中的酶与 RNA 世界中的酶之间的相似之处，以及核酸酶对生物技术的新兴影响和医学。 会议的亲密形式旨在促进研究 RNA 和 DNA 酶各个方面的研究人员之间自由交流信息和想法，从而加快这两个领域的研究。