Design and Synthesis of New Chiral Heterogeneous Photocatalysts for Light-Driven Asymmetric Organocatalysis

用于光驱动不对称有机催化的新型手性多相光催化剂的设计与合成

• 批准号: 2889130
• 金额: --
• 依托单位: University of Liverpool
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2889130
• 关键词: Design; Synthesis; New; Chiral; Heterogeneous

Photoredox catalysis is an important development in organic synthesis, offering distinct reaction pathways under mild conditions. The ability to perform photoredox reactions with enantioselectivity is particularly important, as highlighted by the award of the 2021 Nobel prize in Chemistry for the development of asymmetric organocatalysis. Most photocatalysts available to synthetic chemists are homogeneous metal-complexes or organic dyes, which raise issues of cost, recyclability, and waste production. Development of heterogeneous organic photocatalysts could address many of these issues but their application in organic synthesis is still in its infancy and underdeveloped. In this project we aim to design and synthesise new chiral heterogeneous photocatalysts for light-driven asymmetric organocatalysis.

光氧化还原催化是有机合成的重要发展，在温和条件下提供了独特的反应途径。进行对映选择性光氧化还原反应的能力尤为重要，2021 年诺贝尔化学奖因开发不对称有机催化而获得的奖项强调了这一点。合成化学家可用的大多数光催化剂都是均质金属络合物或有机染料，这引发了成本、可回收性和废物产生的问题。多相有机光催化剂的开发可以解决其中许多问题，但它们在有机合成中的应用仍处于起步阶段且不发达。在这个项目中，我们的目标是设计和合成用于光驱动不对称有机催化的新型手性异质光催化剂。