Quantitative Chemical Biology

定量化学生物学

• 批准号: 7121935
• 负责人: TOBIAS MEYER
• 金额: $ 27.36万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-30 至 2009-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7121935
• 关键词: NIH Roadmap Initiative tag; analytical method; chemical genetics; chemistry; health science research; health science research support; interdisciplinary collaboration; molecular biology; postdoctoral investigator; predoctoral investigator; training

DESCRIPTION (provided by applicant): Quantitative and chemical approaches to biomedical science are becoming increasingly important in the post-genomic era. Through the completion of multiple sequencing efforts, the scientific community has a panoramic view of nature's genetic 'parts', and it is now challenged with acquiring a functional knowledge of this complex machinery. Achieving this goal will require innovative approaches to biomedical research, and our next generation of scientists will therefore need training that seamlessly integrates quantitative, chemical, and biological methods. This application describes plans by Stanford University to create the Quantitative Chemical Biology (QCB) Program, an interschool initiative that will train predoctoral and postdoctoral students in interdisciplinary research. The QCB Program will be organized around several modules that include an interdepartmental graduate training program, a QCB Fellows program, specialized coursework, seminars and symposia, and two QCB faculty-directed facilities that will support post-genomic research projects. These activities and resources will establish a new paradigm for training young scientists, while synergizing with current programs at Stanford, such as the Bio-X initiative for multidisciplinary research. The University's ultimate goal is the creation of an interdepartmental, degree-granting QCB Program. In the interim, the Program will target students admitted to the Departments of Molecular Pharmacology and Chemistry who demonstrate an interest in interdisciplinary research, providing them with unrestricted access to nineteen QCB-affiliated laboratories in six academic departments. The QCB Program will also sponsor postdoctoral fellows who work collaboratively with two or more QCB-affiliated faculty members. Through these mechanisms, the QCB Training Program will support a diverse community that fosters interdisciplinary research and collaborative discovery, preparing future scientists for a scientific landscape without boundaries.

描述（由申请人提供）： 在后基因组时代，生物医学的定量和化学方法变得越来越重要。通过完成多次测序工作，科学界对自然界的遗传“部分”有了全景了解，现在面临的挑战是获取这一复杂机制的功能知识。实现这一目标需要创新的生物医学研究方法，因此我们的下一代科学家将需要无缝整合定量、化学和生物方法的培训。该申请描述了斯坦福大学创建定量化学生物学（QCB）计划的计划，这是一项校际计划，旨在培训博士前和博士后学生进行跨学科研究。 QCB 计划将围绕多个模块进行组织，其中包括跨部门研究生培训计划、QCB 研究员计划、专业课程、研讨会和座谈会，以及两个由 QCB 教师指导的设施，以支持后基因组研究项目。这些活动和资源将为培训年轻科学家建立一个新的范式，同时与斯坦福大学当前的项目（例如用于多学科研究的 Bio-X 计划）产生协同作用。 该大学的最终目标是创建一个跨部门、授予学位的 QCB 项目。在此期间，该计划将针对那些对跨学科研究表现出兴趣的分子药理学和化学系录取的学生，为他们提供不受限制地进入六个学术部门的 19 个 QCB 附属实验室的机会。 QCB 计划还将资助与两名或更多 QCB 附属教员合作工作的博士后研究员。通过这些机制，QCB 培训计划将支持多元化的社区，促进跨学科研究和协作发现，为未来的科学家迎接无边界的科学领域做好准备。