Research Symposium on Functional Abdoninal Pain in Children

儿童功能性腹痛研究研讨会

基本信息

批准号：
7405559
负责人：
SAMUEL NURKO
金额：
$ 2.4万
依托单位：
BOSTON CHILDREN'S HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-09-01 至 2008-08-31
项目状态：
已结题

项目摘要

DESCRIPTION (provided by applicant): The First Symposium "New insights into childhood functional abdominal pain and Irritable Bowel Syndrome (IBS): a multidisciplinary approach" is designed to bring together basic and clinical scientists whose major clinical and research interest relates to the pathophysiology, evaluation and treatment of childhood functional abdominal pain, IBS, and related pain syndromes. This Symposium will 1) identify research targets for future studies of pediatric functional gastrointestinal disorders (FGID), 2) foster interaction and information sharing among national and international experts in a variety of relevant disciplines, 3) define the state of the art in the evaluation and treatment of these disorders and 4) establish a consortium for multidisciplinary collaborative studies. Future Symposia will focus on reporting ongoing studies related to pediatric FGID and developing further collaborative projects. This symposium will be held under the auspices of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN). The Symposium will host invited speakers (both senior and junior experts in basic, translational, and clinical research relevant to functional abdominal pain and IBS, as well as in other pain syndromes in children), expert "discussants", junior faculty and trainees. The following are the Overall Goals of the symposium: 1. To bring together basic scientists addressing cellular and molecular aspects of FGID in order to better understand the roles of the central and enteric nervous systems, gastrointestinal smooth muscle and specific cell types in the pathophysiology of functional abdominal pain and IBS 2. To bring together clinician-investigators addressing the genetics, pathophysiology, diagnosis and treatment strategies of functional abdominal pain and IBS in children. 3. To present the perspective of researchers who are leaders in the study of functional abdominal pain and IBS in adults, in order to take advantage of their expertise, and to uncover points of commonality or disparity between the disease mechanisms, clinical presentation and treatment in adults and in children. By identifying the aspects that are more specific to childhood abdominal pain and IBS, specific areas for research will be recommended. 4. To present the latest available information on clinical aspects of other pain syndromes in children, and to provide a forum in which leading clinical investigators of other pain syndromes in children may share their expertise and allow cross-fertilization with those involved in the study of functional abdominal pain, in order to identify common pathways and stimulate collaboration. 5. To provide opportunities for promising young scientists (graduate students, postdoctoral trainees and faculty at an early stages of their career development), female scientists, and underrepresented minorities to discuss their research with established investigators and expert clinicians in the field of functional abdominal pain and IBS. In addition, this forum will provide a unique opportunity for in-depth discussions with invited speakers to stimulate communication between basic and translational/clinical scientists. 6. To develop a research agenda for collaborative studies to define the pathophysiology and treatment strategies for childhood functional abdominal pain. 7. To educate the NASPGHAN membership on the state of the art of functional abdominal pain and IBS in children.

描述（由申请人提供）：第一届研讨会“对儿童功能性腹痛和肠易激综合征（IBS）的新见解：多学科方法”旨在将主要临床和研究兴趣涉及病理生理学的基础和临床科学家聚集在一起，儿童功能性腹痛、IBS 和相关疼痛综合征的评估和治疗。本次研讨会将 1) 确定儿科功能性胃肠病 (FGID) 未来研究的研究目标，2) 促进各个相关学科的国内和国际专家之间的互动和信息共享，3) 确定评估的最新技术水平以及这些疾病的治疗；4) 建立一个多学科合作研究联盟。未来的研讨会将重点报告正在进行的与儿科 FGID 相关的研究并开发进一步的合作项目。本次研讨会将在北美儿科胃肠病学、肝病学和营养学会（NASPGHAN）的赞助下举行。研讨会将邀请受邀演讲者（与功能性腹痛和肠易激综合症以及其他儿童疼痛综合征相关的基础、转化和临床研究方面的高级和初级专家）、专家“讨论者”、初级教师和学员。研讨会的总体目标如下： 1. 汇聚研究 FGID 细胞和分子方面的基础科学家，以便更好地了解中枢神经系统和肠神经系统、胃肠平滑肌和特定细胞类型在 FGID 病理生理学中的作用功能性腹痛和 IBS 2. 汇集临床研究人员，研究儿童功能性腹痛和 IBS 的遗传学、病理生理学、诊断和治疗策略。 3. 介绍成人功能性腹痛和肠易激综合征研究领域的领先研究人员的观点，以利用他们的专业知识，揭示疾病机制、临床表现和治疗之间的共同点或差异点成人和儿童。通过确定儿童腹痛和肠易激综合症更具体的方面，将推荐具体的研究领域。 4. 提供有关儿童其他疼痛综合征临床方面的最新可用信息，并提供一个论坛，让其他儿童疼痛综合征的主要临床研究人员可以分享他们的专业知识，并允许与参与研究的人员相互交流。功能性腹痛，以确定共同途径并刺激协作。 5. 为有前途的年轻科学家（研究生、博士后学员和处于职业发展早期阶段的教师）、女性科学家和代表性不足的少数群体提供机会，与功能性腹痛领域的知名研究人员和专家临床医生讨论他们的研究和肠易激综合症。此外，本次论坛还将提供一个独特的机会，与受邀演讲者进行深入讨论，以促进基础科学家和转化/临床科学家之间的交流。 6. 制定合作研究的研究议程，以确定儿童功能性腹痛的病理生理学和治疗策略。 7. 向 NASPGHAN 成员介绍儿童功能性腹痛和肠易激综合症的最新技术。