Effects of individual behavioral responses on benefits of influenza vaccination

个人行为反应对流感疫苗接种益处的影响

• 批准号: 7248329
• 负责人: Byung-Kwang Yoo
• 金额: $ 10.36万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-15 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7248329
• 关键词: Accounting; Adult; Applications Grants; Behavior; Behavioral; Caring; Child; Clinic; Clinical Medicine; Computer Simulation; Data; Data Analyses; Development; Disease; Economics; Effectiveness; Elderly; Epidemic; Epidemiology; Future; Health; Health Personnel; Hospitalization; Incentives; Individual; Influenza; Influenza vaccination; Knowledge; Mass Media; Medicaid; Medical; Medicare; Modeling; Morals; Pattern; Population; Production; Provider; Public Health; Purpose; Rate; Relative (related person); Reporting; Research; Research Methodology; Research Personnel; Research Training; Seasons; Selection Bias; Socioeconomic Status; Surveys; System; Target Populations; Techniques; Testing; Theoretical model; Time; Training; Travel; Vaccinated; Vaccination; Vaccines; behavior change; beneficiary; career; cost; ethnic minority population; expectation; flu; hazard; health disparity; improved; influenza epidemic; influenza virus vaccine; insight; interest; models and simulation; mortality; pandemic disease; programs; response; skills; statistics; theories; vaccine effectiveness

DESCRIPTION (provided by applicant): Research on the control of influenza has traditionally been conducted within the paradigm of epidemiology, with little involvement of economics. The purpose of this K25 grant proposal is to develop a didactic training and research program that will enable Dr. Byung-Kwang Yoo to become an independent investigator in economic epidemiology of vaccine-preventable diseases, particularly influenza. Economic epidemiology aims at offering unique insights to the current epidemiology-dominated paradigm through incorporating economic theory and econometric techniques. Dr. Yoo is particularly interested in two quantitative issues regarding influenza vaccination behavior: (i) how individual behavioral patterns respond to external factors such as limited vaccine supply and epidemic levels, and (ii) effects of such behavioral responses on the population-wide benefits of influenza vaccination programs. Trained as a health economist, Dr. Yoo has strong quantitative skills in addition to his background in clinical medicine and public health. The career development part of the K25 grant proposal will enable him to strengthen his quantitative skills in economics (e.g., dynamic modeling) and statistics (e.g., panel data analysis and computer simulation) as well as to gain more knowledge on child influenza vaccination and vaccine distribution/production systems. The specific aims of this method research program are: 1) To develop a dynamic theoretical model for predicting influenza epidemics and individual influenza vaccination receipt and timing, emphasizing potential negative individual incentives incurred by the observations of (i) a lower epidemic level or (ii) a high population flu vaccination coverage level; 2) To conduct empirical analyses among Medicare elderly (a) to examine the determinants of flu vaccination receipt and its timing, including vaccine supply delay/shortage, current and prior epidemic levels, mass media reports, travel time cost to a clinic, and reimbursement rates for health care providers, (b) to explore if vaccine shortage exacerbates health disparities in vaccination receipt and its timing (e.g., the later the worse), (c) to examine influenza vaccine effectiveness in reducing flu-related hospitalization and mortality, adjusting for self-selection bias, e.g., the sicker elderly are more likely to be vaccinated; 3) To construct computer simulation models for predicting the population-wide benefits of influenza vaccination programs targeting all children and the non-elderly adult population.

描述（由申请人提供）：流感控制的研究传统上是在流行病学范式内进行的，很少涉及经济学。这项 K25 拨款提案的目的是开发一项教学培训和研究计划，使 Byung-Kwang Yoo 博士能够成为疫苗可预防疾病（特别是流感）经济流行病学的独立研究者。经济流行病学旨在通过结合经济理论和计量经济学技术，为当前流行病学主导的范式提供独特的见解。 Yoo 博士对有关流感疫苗接种行为的两个定量问题特别感兴趣：(i) 个人行为模式如何应对疫苗供应有限和流行水平等外部因素，以及 (ii) 这种行为反应对全民受益的影响流感疫苗接种计划。 Yoo 博士接受过健康经济学家培训，除了临床医学和公共卫生方面的背景外，还拥有强大的定量技能。 K25拨款提案的职业发展部分将使他能够加强经济学（例如动态建模）和统计学（例如面板数据分析和计算机模拟）方面的定量技能，并获得更多有关儿童流感疫苗接种和疫苗的知识分销/生产系统。该方法研究计划的具体目标是：1）开发一个动态理论模型，用于预测流感流行以及个人流感疫苗接种的接受和时间，强调观察到（i）较低的流行水平或（ii）潜在的负面个人激励) 人口流感疫苗接种覆盖率高； 2) 对医保老年人进行实证分析 (a) 探讨流感疫苗接种及其时机的决定因素，包括疫苗供应延迟/短缺、当前和以往的流行水平、大众媒体报道、前往诊所的交通时间成本和报销(b) 探讨疫苗短缺是否加剧了疫苗接种接种及其时间方面的健康差异（例如，越晚越差），(c) 检查流感疫苗在减少流感相关住院率和死亡率方面的有效性，调整对于自我选择偏差，例如，病情较重的老年人更有可能接种疫苗； 3) 构建计算机模拟模型，用于预测针对所有儿童和非老年人群的流感疫苗接种计划对全民的益处。