Effects of individual behavioral responses on benefits of influenza vaccination

个人行为反应对流感疫苗接种益处的影响

• 批准号: 7616079
• 负责人: Byung-Kwang Yoo
• 金额: $ 10.86万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-15 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7616079
• 关键词: Accounting; Adult; Applications Grants; Award; Behavior; Behavioral; Caring; Centers for Disease Control and Prevention (U.S.); Child; Clinic; Clinical Medicine; Computer Simulation; Data; Data Analyses; Disease; Economics; Elderly; Epidemic; Epidemiology; Foundations; Funding; Future; Health; Health Personnel; Hospitalization; Incentives; Individual; Influenza; Influenza vaccination; Knowledge; Mass Media; Medicaid; Medical; Medicare; Modeling; Morals; Pattern; Population; Production; Provider; Public Health; Relative (related person); Reporting; Research; Research Methodology; Research Personnel; Research Training; Seasons; Selection Bias; Surveys; System; Target Populations; Techniques; Testing; Theoretical model; Time; Training; Travel; Vaccinated; Vaccination; Vaccines; behavior change; beneficiary; career development; cost; ethnic minority population; expectation; flu; hazard; health disparity; improved; influenza epidemic; influenza virus vaccine; insight; interest; low socioeconomic status; mathematical model; models and simulation; mortality; pandemic disease; programs; response; skills; statistics; theories; vaccine effectiveness

DESCRIPTION (provided by applicant): Research on the control of influenza has traditionally been conducted within the paradigm of epidemiology, with little involvement of economics. The purpose of this K25 grant proposal is to develop a didactic training and research program that will enable Dr. Byung-Kwang Yoo to become an independent investigator in economic epidemiology of vaccine-preventable diseases, particularly influenza. Economic epidemiology aims at offering unique insights to the current epidemiology-dominated paradigm through incorporating economic theory and econometric techniques. Dr. Yoo is particularly interested in two quantitative issues regarding influenza vaccination behavior: (i) how individual behavioral patterns respond to external factors such as limited vaccine supply and epidemic levels, and (ii) effects of such behavioral responses on the population-wide benefits of influenza vaccination programs. Trained as a health economist, Dr. Yoo has strong quantitative skills in addition to his background in clinical medicine and public health. The career development part of the K25 grant proposal will enable him to strengthen his quantitative skills in economics (e.g., dynamic modeling) and statistics (e.g., panel data analysis and computer simulation) as well as to gain more knowledge on child influenza vaccination and vaccine distribution/production systems. The specific aims of this method research program are: 1) To develop a dynamic theoretical model for predicting influenza epidemics and individual influenza vaccination receipt and timing, emphasizing potential negative individual incentives incurred by the observations of (i) a lower epidemic level or (ii) a high population flu vaccination coverage level; 2) To conduct empirical analyses among Medicare elderly (a) to examine the determinants of flu vaccination receipt and its timing, including vaccine supply delay/shortage, current and prior epidemic levels, mass media reports, travel time cost to a clinic, and reimbursement rates for health care providers, (b) to explore if vaccine shortage exacerbates health disparities in vaccination receipt and its timing (e.g., the later the worse), (c) to examine influenza vaccine effectiveness in reducing flu-related hospitalization and mortality, adjusting for self-selection bias, e.g., the sicker elderly are more likely to be vaccinated; 3) To construct computer simulation models for predicting the population-wide benefits of influenza vaccination programs targeting all children and the non-elderly adult population.

描述（由申请人提供）：传统上对流感控制的控制进行了研究，在流行病学的范式内进行，很少参与经济学。这项K25赠款提案的目的是制定一项教学培训和研究计划，该计划将使Byung-Kwang Yoo博士能够成为疫苗可预除疾病的经济流行病学独立研究者，尤其是流感。经济流行病学旨在通过结合经济理论和计量经济学技术来为当前流行病学主导的范式提供独特的见解。 Yoo博士对有关流感疫苗接种行为的两个定量问题特别感兴趣：（i）个体行为模式如何应对外部因素，例如有限的疫苗供应和流行性水平，以及（ii）此类行为反应对流感疫苗疫苗疫苗疫苗范围的益处的影响。 Yoo博士受过卫生经济学家的培训，除了他在临床医学和公共卫生方面的背景外，还具有强大的定量技能。 K25赠款提案的职业发展部分将使他能够增强他在经济学（例如动态建模）和统计数据（例如面板数据分析和计算机模拟）方面的定量技能，并获得有关儿童流感疫苗接种和疫苗分配系统的更多知识。该方法研究计划的具体目的是：1）开发一个动态理论模型，以预测流感流行病和个体流感疫苗接种的收到和时机，强调了（i）较低的流行性水平或（ii）高种群疫苗接种水平的潜在负面个人激励措施； 2) To conduct empirical analyses among Medicare elderly (a) to examine the determinants of flu vaccination receipt and its timing, including vaccine supply delay/shortage, current and prior epidemic levels, mass media reports, travel time cost to a clinic, and reimbursement rates for health care providers, (b) to explore if vaccine shortage exacerbates health disparities in vaccination receipt and its timing (e.g., the later更糟的是），（c）检查流感疫苗在降低流感相关的住院和死亡率方面的有效性，调整自我选择偏见，例如，病人更有可能接种疫苗的老年人； 3）构建计算机仿真模型，以预测针对所有儿童和非老年人人群的流感疫苗接种计划的人口益处。