Minimizing Instability with Dynamic Visual Inputs

通过动态视觉输入最大限度地减少不稳定性

基本信息

批准号：
7162947
负责人：
Emily A Keshner
金额：
$ 31.72万
依托单位：
TEMPLE UNIV OF THE COMMONWEALTH
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
起止时间：
2003-01-13 至 2008-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7162947
关键词：
Bilateral Body Weight Changes Complex Condition Dependence Disease Distant Effectiveness Effectiveness of Interventions Environment Equilibrium Feedback Financial compensation Frequencies Functional disorder Gait abnormality Goals Head Individual Instruction Intervention Lateral Learning Link Locomotion Lower Extremity Measures Methods Motion Musculoskeletal Equilibrium Pathway interactions Patients Pattern Performance Peripheral Photic Stimulation Postural response Principal Investigator Protocols documentation Range Reliance Sensory Simulate Space Perception System Techniques Testing Texture Therapeutic Intervention Training Training Programs Vestibular loss Visual Visual Fields Visual Motion Visual system structure Walking Weight day improved insight pressure programs response retinal rods virtual visual feedback visual information visual-vestibular

项目摘要

The long-term goal of this project is to understand how balance and gait disorders can be helped by using dynamic visual environments to facilitate sensorimotor relearning during locomotion and stance postural control. When vestibular inputs become unreliable, either from labyrinthine loss or dysfunction, individuals must learn to rely upon visual and proprioceptive pathways to produce appropriate responses for changes in postural orientation or equilibrium. Attempts to produce sensory relearning through practicing postural and purposeful activities in static environments have not proved to be a fully successful intervention, possibly because the controlled inputs do not place the necessary demands on the functionality of the postural system. Individuals may become fixed on one pattem of response and be unable to match the range of disturbances encountered in the environment. We propose to study changes in postural responses and spatial orientation during locomotion within a dynamic visual environment in normal subjects and in patients with bilateral labyrinthine loss. We hypothesize that individuals _ with vestibular loss become fixed on one strategy of compensation and can not compensate for the fluctuating demands of a dynamic environment. We will examine whether providing strategies for using visual information assists these individuals in compensating for destabilization. Subjects will be tested during quiet stance and walking on a treadmill while we manipulate the velocity or contextual contrast of a dynamic virtual environment. Segmental excursions and center of pressure will be measured and analyzed with repeated measures ANOVAs to determine if postural organization and orientation is influenced by specific parameters of the peripheral field of view. The parameters that emerge as most destabilizing will be applied in a training program where subjects will be instructed to focus on a distant target or on internal feedback to determine if active performance in a dynamic visual environment increases the response repertoire of individuals with labyrinthine loss. Finally, we will assess whether there is functional carryover from training within a dynamic visual environment. Subjects will perform a simulated physical world task in which they must retrieve and place an object while the world moves around them and obstacles appear in their path. Results from these studies will provide insight into the dynamics of the visual- vestibular interaction and identify specific quantitative protocols for therapeutic interventions with balance disorders.

该项目的长期目标是了解如何通过使用来帮助平衡和步态障碍动态视觉环境可促进运动和站立姿势控制期间的感觉运动重新学习。当前庭输入因迷路丢失或功能障碍而变得不可靠时，个体必须学会依靠视觉和本体感觉通路对姿势方向的变化产生适当的反应或平衡。尝试通过练习姿势和有目的的活动来重新学习感觉静态环境尚未被证明是完全成功的干预，可能是因为受控输入确实不对姿势系统的功能提出必要的要求。个人可能会固定于一个响应模式并且无法匹配环境中遇到的干扰范围。我们建议研究动态视觉中运动过程中姿势反应和空间方向的变化正常受试者和双侧迷路丢失患者的环境。我们假设个人 _ 前庭损失变得固定于一种补偿策略，并且无法补偿波动的动态环境的要求。我们将研究是否提供使用视觉信息的策略帮助这些人补偿不稳定的情况。受试者将在安静的姿势和在跑步机上行走，同时我们操纵动态虚拟环境的速度或上下文对比度。将通过重复测量方差分析来测量和分析分段偏移和压力中心，以确定姿势组织和方向是否受到周围场特定参数的影响看法。最不稳定的参数将应用于培训计划，其中受试者将指示专注于远处的目标或内部反馈，以确定动态视觉中的主动表现环境增加了迷路丧失患者的反应能力。最后，我们将评估是否在动态视觉环境中进行的训练会产生功能性的遗留影响。受试者将进行模拟物理世界任务，他们必须在世界围绕他们移动时检索并放置一个物体，并且他们的道路上出现了障碍。这些研究的结果将提供对视觉动态的深入了解前庭相互作用并确定平衡治疗干预的具体定量方案失调。