Minimizing Instability with Dynamic Visual Inputs

通过动态视觉输入最大限度地减少不稳定性

• 批准号: 6839993
• 负责人: Emily A Keshner
• 金额: $ 26.85万
• 依托单位: REHABILITATION INSTITUTE OF CHICAGO D/B/A SHIRLEY RYAN ABILITYLAB
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-01-13 至 2007-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6839993
• 关键词: Minimizing; Instability; Dynamic; Visual; Inputs

EXCEED THE SPACE PROVIDED. The long-term goal of this project is to understand how balance and gait disorders can be helped by using dynamic visual environments to facilitate sensorimotor relearning during locomotion and stance postural control. When vestibular inputs become unreliable, either from labyrinthine loss or dysfunction, individuals must learn to rely upon visual and proprioceptive pathways to produce appropriate responses for changes in postural orientation or equilibrium. Attempts to produce sensory relearning through practicing postural and purposeful activities in static environments have not proved to be a fully successful intervention, possibly because the controlled inputs do not place the necessary demands on the functionality of the postural system. Individuals may become fixed on one pattem of response and be unable to match the range of disturbances encountered in the environment. We propose to study changes in postural responses and spatial orientation during locomotion within a dynamic visual environment in normal subjects and in patients with bilateral labyrinthine loss. We hypothesize that individuals _ with vestibular loss become fixed on one strategy of compensation and can not compensate for the fluctuating demands of a dynamic environment. We will examine whether providing strategies for using visual information assists these individuals in compensating for destabilization. Subjects will be tested during quiet stance and walking on a treadmill while we manipulate the velocity or contextual contrast of a dynamic virtual environment. Segmental excursions and center of pressure will be measured and analyzed with repeated measures ANOVAs to determine if postural organization and orientation is influenced by specific parameters of the peripheral field of view. The parameters that emerge as most destabilizing will be applied in a training program where subjects will be instructed to focus on a distant target or on internal feedback to determine if active performance in a dynamic visual environment increases the response repertoire of individuals with labyrinthine loss. Finally, we will assess whether there is functional carryover from training within a dynamic visual environment. Subjects will perform a simulated physical world task in which they must retrieve and place an object while the world moves around them and obstacles appear in their path. Results from these studies will provide insight into the dynamics of the visual- vestibular interaction and identify specific quantitative protocols for therapeutic interventions with balance disorders. PERFORMANCE SITE ========================================Section End===========================================

超过提供的空间。 该项目的长期目标是了解如何通过使用动态视觉环境来促进运动和立场姿势控制期间的感觉运动重新学习如何帮助平衡和步态障碍。当前庭输入变得不可靠时，无论是迷宫损失还是功能障碍，个人都必须学会依靠视觉和本体感受途径来产生适当的反应，以改变姿势方向或平衡的变化。试图通过在静态环境中练习姿势和有目的的活动来产生感官重新学习并不是完全成功的干预措施，这可能是因为受控的输入并没有对姿势系统功能提出必要的要求。个体可能会固定在一个响应的捕捉上，并且无法匹配环境中遇到的干扰范围。我们建议研究正常受试者和双侧迷宫丧失患者的动态视觉环境中运动过程中姿势反应和空间取向的变化。我们假设患有前庭损失的个体固定在一种补偿策略上，无法弥补动态环境的波动需求。我们将研究是否提供使用视觉信息的策略有助于这些人补偿不稳定。当我们操纵动态虚拟环境的速度或上下文对比时，将在安静的立场和在跑步机上行走时对受试者进行测试。将通过重复测量方差分析测量和分析分段的偏移和压力中心，以确定姿势组织和方向是否受外围视野的特定参数影响。出现作为大多数不稳定的参数将在训练计划中应用，其中将指示受试者专注于遥远的目标或内部反馈，以确定动态视觉环境中的主动性能是否会增加迷宫般损失的人的响应库。最后，我们将评估在动态视觉环境中训练中是否有功能性结转。受试者将执行模拟的物理世界任务，在世界上，他们必须检索并放置一个物体，而世界则围绕它们移动，并且障碍物出现在他们的道路上。这些研究的结果将洞悉视觉互动的动力学，并确定用于平衡疾病的治疗干预措施的特定定量方案。表演网站=================================== ==================================