Wireless, Low-Maintenance Transdermal Alcohol Sensor

无线、低维护透皮酒精传感器

• 批准号: 7281935
• 负责人: LINDA A TEMPELMAN
• 金额: $ 4.5万
• 依托单位: GINER, INC.
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-27 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7281935
• 关键词: alcoholic beverage consumption; automated data processing; behavioral /social science research tag; bioengineering /biomedical engineering; biomedical equipment development; biosensor device; blood tests; breath tests; clinical research; clinical trials; cost effectiveness; electrochemistry; ethanol; field study; human subject; interview; oxidation; patient oriented research; portable biomedical equipment; questionnaires; substance abuse related behavior; telecommunications; vapor; wrist

DESCRIPTION (provided by applicant): Measurement of transdermal alcohol is potentially a very unobtrusive, inexpensive and accurate way of continuously studying the alcohol consumption behavior of subjects in research and field settings as well as for monitoring special populations. Several innovative technological advances in electrochemical sensing and engineering are proposed that will result in a novel transdermal alcohol sensing system to measure blood alcohol concentration. The proposed sensing system will go beyond the current Giner patented technology and constitute new, innovative, and potentially patentable technology. The new sensor system in the Giner WrisJAS(tm) rWristworn Transdermal Alcohol Sensor) family will require low maintenance, be more comfortable to wear, allow transfer of data from the home, be more resistant to tampering and be less expensive to manufacture. It detects blood alcohol transdermally (10- >400 mg/dl). The commercial goal is to sell the complete alcohol monitoring system for under $ 1100. The proposed Phase II program will continue and extend the successful research and development in the Phase I program. The Phase II objectives are to: 1) Complete Additional Refinements to Enhance Performance and Economy of Sensor Features 2) Develop Second Generation of Wireless Data Transmittal and Automated Data Analysis. 3) Design WrisTAS(tm) 7 Enclosures (sensor module, electronics module and wristband/cable) 4) Evaluate the New WrisTAS(tm) Products in Clinical Settings. Commercial Potential: There are a number of markets for a continuous, nohinvasive alcohol monitor including: 1) Research and clinical treatment programs. 2) Emergency room setting for individuals that are unconscious, incapacitated, or unable to exhale forcibly. 3) Monitoring of professionals with or without known alcohol problems in positions involving public safety (aviation, nuclear, medical). 4) Monitoring drivers with prior DWI/DUI convictions. 5) Criminal justice system, where the court needs to monitor alcohol abstinence of convicted criminals on parole, probation or house arrest.

描述（由申请人提供）：透皮酒精测量可能是一种非常不引人注目、廉价且准确的方法，可用于持续研究研究和现场环境中受试者的饮酒行为以及监测特殊人群。电化学传感和工程领域提出了几项创新技术进步，这将产生一种新型的透皮酒精传感系统来测量血液酒精浓度。拟议的传感系统将超越当前 Giner 的专利技术，并构成新的、创新的、潜在的专利技术。 Giner WrisJAS(tm) rWristworn 透皮酒精传感器) 系列中的新型传感器系统需要很少的维护、佩戴更舒适、允许在家中传输数据、更耐篡改并且制造成本更低。它经皮检测血液中的酒精含量 (10->400 mg/dl)。商业目标是以低于 1100 美元的价格出售完整的酒精监测系统。 拟议的第二阶段计划将继续并扩展第一阶段计划的成功研究和开发。第二阶段的目标是： 1) 完成额外的改进，以增强传感器功能的性能和经济性 2) 开发第二代无线数据传输和自动数据分析。 3) 设计 WrisTAS(tm) 7 外壳（传感器模块、电子模块和腕带/电缆） 4) 在临床环境中评估新的 WrisTAS(tm) 产品。 商业潜力：连续、无创酒精监测仪有许多市场，包括： 1) 研究和临床治疗项目。 2) 为失去知觉、丧失能力或无法用力呼气的人员设置急诊室。 3) 对涉及公共安全（航空、核、医疗）的岗位上有或没有已知酒精问题的专业人员进行监测。 4) 监控有酒驾/酒驾前科的司机。 5）刑事司法系统，法院需要对假释、缓刑或软禁的已定罪罪犯的戒酒情况进行监督。