ACTIVITY 5: CORE SUPPORT

活动 5：核心支持

• 批准号: 7336071
• 负责人: PATRICIA A COUVILLON
• 金额: $ 0.84万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-17 至 2007-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7336071
• 关键词: DNA; Hawaii; bioinformatics; computer network; computers; data management; functional /structural genomics; genotype; medicine; molecular biology; molecular genetics; nucleic acid sequence; oligonucleotides; pathology; personal computers; proteomics; schools; training; university

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary goal of the Core Support activity is the development of state-of-the-art facilities to directly support the RCMI research activities. The secondary goal is to upgrade the infrastructure for biological, biomedical and biotechnological research at the University of Hawaii at Manoa. The three core facilities are the Molecular Biology Core Facility (MBCF), the Computer Network Support Facility (CNSF), both in the Pacific Biosciences Research Center and the Biostatistics and Data Management Facility (BDMF) in the School of Medicine. Both the molecular and computer facilities were established units, but were in need of expansion to exploit the rapid technological advances in these fields. The biostatistics facility was created in 2004 with RCMI support to meet the growing needs of researchers whose current and potential extramural research support requires expert biostatistical consultation and services. The specific aims of the Molecular Biology Core Facility are 1) to provide efficient and cost-effective DNA sequencing, oligonucleotide synthesis, genotyping, DNA microarray analysis and bioinformatics services, and 2) to develop progressive expertise in emerging research and applied technologies, including structural and functional genomics and proteomics and molecular genetic pathology. The specific aims of the Computer Network Support Facility are 1) to expand network capability to include dedicated research servers and web-based applications for data access by collaborating researchers, and 2) to manage the desktop and laptop computers of individual researchers with hardware, software, security, peripherals and training support. The specific aims of the Biostatistics and Data Management Facility are 1) to provide statistical and data management consultation and services to clinical and basic researchers, initially to those with the RCMI program, and 2) to establish the facility as an ongoing core resource available to all biomedical researchers at UHM.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。核心支持活动的主要目标是开发直接支持RCMI研究活动的最先进的设施。第二个目标是升级Manoa夏威夷大学生物，生物医学和生物技术研究的基础设施。这三个核心设施是分子生物学核心设施（MBCF），计算机网络支持设施（CNSF），包括在太平洋生物科学研究中心以及医学院的生物统计学和数据管理设施（BDMF）。分子和计算机设施均建立了单位，但需要扩展以利用这些领域的快速技术进步。生物统计学设施是在2004年创建的，以RCMI的支持，以满足研究人员不断增长的需求，这些研究人员的目前和潜在的壁外研究支持需要专家生物统计学咨询和服务。分子生物学核心设施的具体目的是1）提供有效且具有成本效益的DNA测序，寡核苷酸合成，基因分型，DNA微阵列分析和生物信息传染性服务以及2）2）在结构和功能性遗传学和植物学概念和植物学中，在出现的研究和应用技术方面开发了进步的专业知识。计算机网络支持设施的具体目的是1）扩展网络能力，以包括协作研究人员的专用研究服务器和基于Web的基于Web的应用程序，以及2）管理具有硬件，软件，安全性，外围设备和培训支持的个别研究人员的台式机和笔记本电脑。生物统计学和数据管理设施的具体目的是1）为临床和基础研究人员提供统计和数据管理咨询和服务，最初是向RCMI计划的人提供的，以及2）将该设施确立为UHM所有生物医学研究人员的持续核心资源。