Cone-Beam Tomography with Truncated Projections

截断投影的锥束断层扫描

基本信息

批准号：
7025043
负责人：
Frederic Noo
金额：
$ 25.19万
依托单位：
UNIVERSITY OF UTAH
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-05-15 至 2008-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7025043
关键词：
bioimaging /biomedical imaging biomedical automation computed axial tomography computer program /software computer system design /evaluation high throughput technology image enhancement mathematical model mathematics model design /development phantom model technology /technique development

项目摘要

DESCRIPTION (provided by applicant): The long term objective of this project is to solve the truncation problem in cone-beam tomography, and to implement and freely distribute image reconstruction software suitable for the most common cone-beam imaging configurations. The specific aims are: 1) to devise, implement, and make publicly available, fast accurate image reconstruction code for cone-beam computed tomography (CBCT) geometries where the source and detector rotate once (or slightly more than once) about the patient, and the projections are always truncated axially (and may also be truncated transaxially), 2) to devise, implement, and make publicly available, fast accurate image reconstruction code for CBCT geometries tailored to C-arm based CT with projections measured over an angular range of about 180 degrees, and with relevant patterns of truncation, and 3) to design and implement simple practical calibration methods from which geometric reconstruction parameters are automatically obtained and passed to the reconstruction algorithms for the scanner configurations of aims 1 and 2. The methods involve devising algorithms that are impervious to the propagation of false information that is normally concomitant with truncated projection data. Six cone-beam configurations will be considered, and algorithms will be devised by assembling fundamental mathematical tools which have been successful in solving certain specific cone-beam truncation problems in the past. The algorithms will be tested with computer simulated data and phantom measurements from benchtop and physical scanners. Automated calibration will be devised by extending existing analytic approaches, and tested against chi-squared approaches using simulated and real data. The health benefits of this project relate to the transition of cone-beam tomography from its current status as primarily a high-contrast imaging tool to a fast, quantitative, volume imaging modality with widespread applications in image guidance and diagnosis.

描述（由申请人提供）：该项目的长期目标是解决锥形束断层扫描中的截断问题，并实现和自由分发适合最常见的锥形梁成像配置的图像重建软件。 The specific aims are: 1) to devise, implement, and make publicly available, fast accurate image reconstruction code for cone-beam computed tomography (CBCT) geometries where the source and detector rotate once (or slightly more than once) about the patient, and the projections are always truncated axially (and may also be truncated transaxially), 2) to devise, implement, and make publicly available, fast accurate image reconstruction code for CBCT针对基于C-ARM的CT量身定制的几何形状，其在大约180度的角度范围内测量，并具有相关的截短模式，以及3）设计和实施简单的实用校准方法，从中自动获得几何重建参数，并传递给重建算法的算法，以适用于scanner cannernner配置的重建算法。这些方法涉及设计算法，这些算法与通常与截断的投影数据相关的虚假信息的传播不渗透。将考虑六个锥形梁配置，并通过组装基本的数学工具来设计算法，这些工具成功地解决了过去解决某些特定的锥形梁截断问题。该算法将通过计算机模拟数据和台面和物理扫描仪的幻影测量进行测试。将通过扩展现有的分析方法来设计自动校准，并使用模拟和真实数据对卡方方法进行测试。该项目的健康益处与锥形束从目前的状态过渡有关，它主要是高对比度成像工具，即在图像指导和诊断中广泛应用的快速，定量，体积成像模态。

项目成果

期刊论文数量（9）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Direct determination of geometric alignment parameters for cone-beam scanners.

DOI：
10.1088/0031-9155/54/6/016
发表时间：
2009-03-21
期刊：
Physics in medicine and biology
影响因子：
3.5
作者：
Mennessier C;Clackdoyle R;Noo F
通讯作者：
Noo F

Quantification of Tomographic Incompleteness in Cone-Beam Reconstruction.

DOI：
10.1109/trpms.2019.2918222
发表时间：
2020-01
期刊：
IEEE transactions on radiation and plasma medical sciences
影响因子：
4.4
作者：
Clackdoyle R;Noo F
通讯作者：
Noo F

Accurate image reconstruction using real C-arm data from a Circle-plus-arc trajectory.

DOI：
10.1007/s11548-011-0607-z
发表时间：
2012-01
期刊：
INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY
影响因子：
3
作者：
Hoppe, Stefan;Hornegger, Joachim;Dennerlein, Frank;Lauritsch, Guenter;Noo, Frederic
通讯作者：
Noo, Frederic

Evaluation of image noise in fan-beam x-ray computed tomography.

扇束 X 射线计算机断层扫描中图像噪声的评估。