Comorbid childhood anxiety and asthma

儿童期焦虑症和哮喘共病

• 批准号: 6711198
• 负责人: RENEE D GOODWIN
• 金额: $ 13.71万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6711198
• 关键词: adolescence (12-20); anxiety; anxiety disorders; asthma; clinical research; comorbidity; disease /disorder proneness /risk; health care service utilization; human subject; longitudinal human study; mental health epidemiology; middle childhood (6-11); patient oriented research; psychopathology; respiratory disorder epidemiology; statistics /biometry

DESCRIPTION (provided by investigator): The applicant is requesting five years of funding through the Mentored Patient-Oriented Research Career Development Award (K23) program to enhance her technical and methodological skills in the investigation of the co-occurrence of anxiety disorders and asthma/allergy in youth. The ultimate goal is to gain expertise in the relationship between the co-occurrence of anxiety disorders and asthma/allergy and the risk of severe psychopathology among youth, using longitudinal, epidemiologic research methodology and ultimately to identify preventive interventions. The applicant's strong academic background in human development, clinical psychology, and psychiatric epidemiology, and her research experience using a developmental paradigm to study risk for severe psychopathology among individuals with early-onset anxiety disorders provide an excellent foundation for this work. The proposed training goals include (1) further training to increase the applicant's knowledge of the relationship between respiratory pathophysiology and anxiety disorders; (2) advanced statistical training and experience with longitudinal data analysis and survey methods, and; (3) investigation of potential interventions that integrate research on anxiety disorders and asthma/allergy. These goals will all facilitate the applicant's pursuit of innovative, comprehensive, technologically efficient approaches to study these comorbidities in youth. The research plan for this Award is divided into four investigations which complement the proposed sequence of training activities and offer the applicant the opportunity to explore important cross-sectional and longitudinal data from epidemiologic clinical and community samples, as well as hands-on experience, in the first two studies, the applicant will analyze previously collected data (MECA & SED and Dunedin). In the third study, the applicant will collect her own asthma data prospectively (Network study), in an ongoing longitudinal epidemiologic clinical (psychiatric) investigation, while learning how to conduct a study. The fourth investigation will involve developing measures and collecting pilot data on asthma and anxiety in a clinical (medical) sample. The applicant's resulting ROl will address the developmental paradigm described above, which will be further tested and will include early intervention strategies to facilitate the identification and treatment of children who are at risk for severe psychopathology. That study will involve a longitudinal epidemiologic preventive intervention study aimed at reducing the risk of anxiety disorders among pediatric asthma/allergy patients.

描述（由研究者提供）：申请人请求通过指导患者导向的研究职业发展提供五年的资助 奖励（K23）计划，以提高她在以下方面的技术和方法技能 焦虑症和哮喘/过敏同时发生的调查 青年。最终目标是获得有关双方关系的专业知识 焦虑症和哮喘/过敏同时发生以及严重的风险 青年精神病理学，利用纵向流行病学研究 方法并最终确定预防性干预措施。这 申请人在人类发展、临床方面具有深厚的学术背景 心理学和精神病学流行病学，以及她使用 研究严重精神病理学风险的发展范式 患有早发性焦虑症的个体提供了良好的基础 为了这项工作。拟议的培训目标包括 (1) 进一步培训 增加申请人对呼吸之间关系的了解 病理生理学和焦虑症； (2) 高级统计培训和 具有纵向数据分析和调查方法的经验； (3) 调查整合焦虑研究的潜在干预措施 疾病和哮喘/过敏。这些目标都将有利于申请人 追求创新、全面、技术高效的方法 研究年轻人的这些合并症。本奖项的研究计划分为 进行四项调查以补充拟议的培训顺序 活动并为申请人提供探索重要内容的机会 来自流行病学临床和社区的横断面和纵向数据 在前两项研究中，样本以及实践经验 申请人将分析之前收集的数据（MECA & SED 和达尼丁）。在 第三项研究，申请人将前瞻性地收集自己的哮喘数据 （网络研究），在一项正在进行的纵向流行病学临床中 （精神病学）调查，同时学习如何进行研究。第四个 调查将涉及制定措施并收集试点数据 临床（医学）样本中的哮喘和焦虑。申请人的结果 ROl将解决上述的发展范式，这将是 进一步测试并将包括早期干预策略，以促进 识别和治疗有严重危险的儿童 精神病理学。该研究将涉及纵向流行病学研究 旨在降低焦虑症风险的预防性干预研究 儿童哮喘/过敏患者。