Treatment adherence in minorities with rheumatic disease

少数风湿病患者的治疗依从性

• 批准号: 7093223
• 负责人: Maria E Suarez-Almazor
• 金额: $ 7.48万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2006-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7093223
• 关键词: African American; Hispanic Americans; adult human (21+); attitude; behavior test; behavioral /social science research tag; belief; caucasian American; clinical research; culture; expectancy; health care model; health care service availability; human subject; longitudinal human study; model design /development; outcomes research; patient care personnel relations; psychological tests; questionnaires; racial /ethnic difference; rheumatoid arthritis; systemic lupus erythematosus; therapy compliance

DESCRIPTION (provided by investigator): The outcome of patients with rheumatic disease, in particular rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) is variable and often unpredictable, and important differences have been observed across racial groups. Patients often show poor adherence to therapy, but the determinants and outcomes of compliance-related behaviors have not been adequately documented. We hypothesize that some of the ethnic differences in the outcome of these diseases may be related to degree of compliance with physician recommendations. The overall objective of this study is to quantify adherence to medical recommendations in patients with RA and SLE from diverse ethnic backgrounds, and to determine which are its predictors and outcomes, with an emphasis on psychosocial factors and medical interaction issues. The study will: a) compare attitudes and behaviors toward adherence to treatment in patients with RA and SLE from diverse ethnic backgrounds; b) assess the role of patient beliefs, expectations and attitudes about their disease on their adherence to treatment; c) assess the role of selected elements of the medical interaction on patients' compliance; d) evaluate ethnic differences in compliance in the context of a modified Health Belief Model (HBM); and e) determine the impact of non-compliance on patient outcomes. Phase I will use focus groups (including White, Hispanic, and Black patients) to explore the views of patients with RA and SLE toward adherence to treatment, barriers and perceived benefits. The groups will also provide information to develop scales that measure barriers and expectations in the context of the HBM. Phase 2 will be a 2-year cohort study of patients with RA and SLE from diverse ethnic backgrounds which will evaluate the determinants of adherence to treatment on the basis of the HBM, and will also examine health outcomes at the end of the 2 years according to the degree of adherence.

描述（调查员提供）：风湿病患者的结果 疾病，特别是类风湿关节炎（RA）和全身性狼疮 红斑（SLE）是可变的，通常是不可预测的，而且很重要 在种族群体之间已经观察到差异。患者经常表现不佳 遵守治疗，但与依从性相关的决定因素和结果 行为尚未得到充分记录。我们假设一些 这些疾病结果的种族差异可能与 遵守医师建议。这项研究的总体目标 是为了量化RA和SLE患者的医疗建议依从性 来自不同种族背景，并确定哪些是其预测因素和 结果，重点是社会心理因素和医疗互动 问题。研究将：a）比较对遵守的态度和行为 来自不同种族背景的RA和SLE患者的治疗； b） 评估患者信念，期望和态度的作用 疾病遵守治疗； c）评估选定的作用 对患者依从性的医疗互动元素； d）评估种族 在改良的健康信念模型的背景下，合规性差异 （HBM）; e）确定不合规对患者预后的影响。阶段 我将使用焦点小组（包括白人，西班牙裔和黑人患者） 探索RA和SLE患者遵守治疗的患者的观点， 障碍和感知的好处。小组还将提供信息 开发衡量障碍和期望的量表 HBM。第2阶段将是一项为期2年的队列研究，对RA和SLE患者的研究 各种种族背景将评估遵守的决定因素 根据HBM进行治疗，还将检查 根据依从性程度的两年结束。