Methods Training in Patient-Centered Cancer Outcomes Research

以患者为中心的癌症结果研究方法培训

• 批准号: 8744508
• 负责人: Maria E Suarez-Almazor
• 金额: $ 49.09万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2019-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8744508
• 关键词: Methods; Training; Patient; Centered; Cancer

DESCRIPTION (provided by applicant): One in three of us will develop cancer during our lifetime. This incidence will increase as the population ages. Advances in medical knowledge have lead to an exponential increase in healthcare options for the prevention, diagnosis and therapy of cancer. Choices among competing alternatives are often difficult because the available evidence may differ among options, and may not reflect values that are important to patients when making healthcare decisions. There is increasing recognition that patient preferences are instrumental in making appropriate decisions for care. Many studies are based on biomedical outcomes that are not easily understood by patients, and often, not well understood either by clinicians or policy-makers. Comparative effectiveness research (CER) aims to inform healthcare decisions by providing evidence on the benefits and harms of different alternatives. CER synthesizes and generates comparable evidence on the effectiveness of interventions so that decision-makers (patients, clinicians and policy-makers) can make informed choices. Patient-centered outcomes research (PCOR) ensures that the evidence gathered through CER is relevant to patients and provides information on outcomes that people care about: survival, symptoms, function and quality of life. This is especially important for patients with cancer since therapies can be effective for some outcomes (e.g. disease- free survival) but deleterious for others (e.g. quality of life affected by treatment toxicity). As CER/PCOR evolves there is increased need for training researchers in this area. For this proposal we have partnered with the American Society of Clinical Oncology (ASCO) to offer training and workforce development opportunities in the field of CER/PCOR in cancer care. The goal of this application is to provide a comprehensive training program for cancer researchers interested in CER/PCOR. We have identified four major interrelated methodology cores for training: (i) Knowledge synthesis and translation; (ii) Observational research and registries; (iii Pragmatic clinical trials and healthcare delivery evaluation; and (iv) Patient-centered outcomes research. Our program will provide different levels of training. Basic learning modules will be implemented through on-demand online lectures and interactive components (Q&A online sessions and methods blog). Advanced methods training will be offered in partnership with ASCO and will include Webinars and hands-on face-to-face educational workshops. Finally, on-site experiential learning for fellows will be provided with specialization in one of the core area identified above. This component will also include a personalized mentoring plan. Our training program will encompass the whole spectrum of cancer care including prevention, cancer treatment and healthcare delivery, supportive care, survivorship, and end-of-life care. The proposed program is unique in the field of cancer research, it will provide innovative peer-to-peer learning opportunities, and will enhance best research practices. The training proposed here will increase the nation's workforce of researchers conducting state-of-the-art CER/PCOR throughout the spectrum of cancer care.

描述（由申请人提供）：三分之一的人在一生中会患上癌症。随着人口老龄化，这种发生率将会增加。医学知识的进步导致癌症预防、诊断和治疗的医疗保健选择呈指数级增长。在竞争性替代方案中做出选择通常很困难，因为可用的证据可能因选项而异，并且可能无法反映对患者做出医疗保健决策时重要的价值观。人们越来越认识到患者的偏好有助于做出适当的护理决定。许多研究都是基于患者不容易理解的生物医学结果，而且临床医生或政策制定者通常也不能很好地理解这些结果。比较有效性研究 (CER) 旨在通过提供不同替代方案的益处和危害的证据来为医疗决策提供信息。 CER 综合并生成有关干预措施有效性的可比证据，以便决策者（患者、临床医生和政策制定者）​​能够做出明智的选择。以患者为中心的结果研究 (PCOR) 确保通过 CER 收集的证据与患者相关，并提供有关人们关心的结果的信息：生存、症状、功能和生活质量。这对于癌症患者尤其重要，因为治疗可能对某些结果有效（例如无病生存），但对其他结果有害（例如受治疗毒性影响的生活质量）。随着 CER/PCOR 的发展，对这一领域研究人员进行培训的需求不断增加。对于这项提案，我们与美国临床肿瘤学会 (ASCO) 合作，提供癌症护理 CER/PCOR 领域的培训和劳动力发展机会。该应用程序的目标是为对 CER/PCOR 感兴趣的癌症研究人员提供全面的培训计划。我们确定了四个主要的相互关联的培训方法核心： (i) 知识合成和翻译； (ii) 观察研究和登记； （iii）务实的临床试验和医疗保健服务评估；以及（iv）以患者为中心的结果研究。我们的计划将提供不同级别的培训。基本学习模块将通过点播在线讲座和互动组件（问答在线课程和方法）来实施将与 ASCO 合作提供高级方法培训，包括网络研讨会和面对面的实践教育研讨会，最后将为研究员提供针对所确定的核心领域之一的专业化现场体验式学习。多于。该部分还将包括个性化指导计划，涵盖癌症护理的各个方面，包括预防、癌症治疗和医疗保健提供、支持性护理、生存和临终关怀。在癌症研究领域，它将提供创新的同行学习机会，并将增强最佳研究实践。这里提出的培训将增加国家的研究人员队伍，在整个癌症护理领域进行最先进的 CER/PCOR。