Core--Gene Marker and Sequencing

核心——基因标记与测序

• 批准号: 7028177
• 负责人: RICHARD C DAVIS
• 金额: $ 17.77万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2010-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7028177
• 关键词: animal genetic material tag; biomedical facility; genetic mapping; genetic markers; human genetic material tag; nucleic acid sequence; single nucleotide polymorphism

The role for this core is to support all the projects in their requirements for single nucleotide polymorphism (SNP)1 analysis, gene mapping and sequencing. Support will be provided by several means with emphasis placed on: 1) High volume scoring of SNP and microsatellite polymorphisms in humans and mice; and 2) the processing and analysis of dideoxy-terminated sequencing reactions produced by the individual projects. In addition, the core will aid the projects in the preparation of genotype and sequence data in formats most useful for further analysis. Human mapping data will be formatted for forwarding to the Bioslatistics Core.

该核心的作用是支持所有项目对单核苷酸的需求 多态性 (SNP)1 分析、基因定位和测序。将通过多种方式提供支持，重点是： 1）人类和小鼠中 SNP 和微卫星多态性的大量评分； 2) 各个项目产生的双脱氧终止测序反应的处理和分析。此外，该核心将帮助项目准备基因型和序列数据，其格式对进一步分析最有用。人类绘图数据将被格式化以转发到生物统计核心。