Preventing HIV Among IDUs in Yaroslavl Russia

俄罗斯雅罗斯拉夫尔市注射吸毒者预防艾滋病毒

• 批准号: 6552645
• 负责人: ROBERT S BROADHEAD
• 金额: $ 32.29万
• 依托单位: UNIVERSITY OF CONNECTICUT STORRS
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-25 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6552645
• 关键词: AIDS education /prevention; Commonwealth of Independent States; HIV infections; behavioral /social science research tag; clinical research; cognitive behavior therapy; health care service utilization; human subject; injection /infusion; interview; intravenous drug abuse; longitudinal human study; peer group; social support network

DESCRIPTION (provided by applicant): The efficacy of a peer-driven intervention (PDI), compared to a traditional outreach project, to combat the spread of HIV among injection drug users (IDUs) was demonstrated in a multi-site study from 1994-1998 in eastern Connecticut, directed by the PI of this proposal and funded by NlDA (R01 DA08014). The feasibility of a PDI in Russia to recruit and educate IDUs for HIV prevention was successfully demonstrated in a one- site study from 1996-1998, funded by the International Harm Reduction Development Program of the Open Society Institute, New York City. Further research is now required to improve the PDI model for further use in both the U.S. and abroad. We propose comparing a standard-PDI to a simplified-PDI in terms of recruitment power and educational efficacy to reduce IDU-risk behaviors in two sites in the oblast (province) of Yaroslavl, Russia: Bragino and Rybinsk. The goal is to recruit 500 IDUs at each site for a baseline and three, six-month follow-up health and risk assessment interviews. At both sites, IDUs will be offered recruitment coupons and nominal rewards to educate their peers in the community and recruit them to a project storefront. Each of their recruits will also be given the same education and recruitment opportunity. At three, six-month intervals all subjects will be given the opportunity to re-access and educate each of their original recruits in a new body of prevention information, and to re-recruit them to the project in each city for follow-up interviews and services. In the standard-PDI, subjects will be offered separate, nominal rewards for recruiting peers for services, and for educating them in the community. In the simplified-PDI, the subjects will be offered a flat reward for both educating and recruiting subjects. This modification will streamline the model's operation and make it less expensive, which will be advantageous if the simplified-PDI compares favorably with the standard-PDI in terms of recruitment power and educational effectiveness. The proposed study offers the United States an opportunity to improve the PDI model for more effective use at home while offering Russia urgently needed HIV prevention assistance to hundreds of IDUs in two different cities. The study is also in response to NIH's Global AIDS Research Initiative and Strategic Plan, established by the Office of AIDS Research for fiscal year 2003.

描述（由申请人提供）：与传统的外展项目相比，同伴驱动的干预（PDI）在对抗注射吸毒者（IDU）中艾滋病毒传播方面的有效性在 1994 年的一项多中心研究中得到了证明。 1998 年在康涅狄格州东部，由该提案的 PI 指导并由 NlDA (R01 DA08014) 资助。 1996 年至 1998 年的一项现场研究成功证明了俄罗斯 PDI 招募和教育注射吸毒者以预防艾滋病毒的可行性，该研究由纽约市开放社会研究所国际减少危害发展计划资助。现在需要进一步研究来改进 PDI 模型，以便在美国和国外进一步使用。我们建议在俄罗斯雅罗斯拉夫尔州（省）的两个地点：布拉吉诺和雷宾斯克，在招募能力和教育功效方面对标准 PDI 和简化 PDI 进行比较，以减少注射吸毒者风险行为。目标是在每个地点招募 500 名注射吸毒者进行基线访谈和为期 3 个月、为期 6 个月的后续健康和风险评估访谈。在这两个网站，注射吸毒者都将获得招募优惠券和象征性奖励，以教育社区中的同行并招募他们进入项目店面。他们的每个新兵也将获得相同的教育和招聘机会。每隔三到六个月，所有受试者将有机会重新接触和教育每一位最初招募的人员，了解新的预防信息，并重新招募他们到每个城市的项目进行后续访谈和服务。在标准 PDI 中，受试者将因招募同伴提供服务以及在社区中对他们进行教育而获得单独的名义奖励。在简化的 PDI 中，将为教育和招募受试者提供固定奖励。这一修改将简化模型的操作并降低成本，如果简化 PDI 在招募能力和教育效果方面与标准 PDI 相比，这将是有利的。拟议的研究为美国提供了一个改进 PDI 模型的机会，以便在国内更有效地使用，同时为俄罗斯两个不同城市的数百名注射吸毒者提供急需的艾滋病毒预防援助。该研究也是对 NIH 全球艾滋病研究倡议和战略计划的响应，该计划由艾滋病研究办公室在 2003 财年制定。