TRAINING PROGRAM IN CLINICAL RESEARCH

临床研究培训计划

• 批准号: 6756530
• 负责人: DAVID Eduardo SCHTEINGART
• 金额: $ 20万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-06-01 至 2005-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6756530
• 关键词: clinical research; curriculum; data collection methodology /evaluation; education evaluation /planning; epidemiology; ethics; experimental designs; health science research potential; informatics; interdisciplinary collaboration; minority health professional; outcomes research; postgraduate education; public health; statistics /biometry; training

The University of Michigan Training Program in Clinical Research will streamline, upgrade and integrate existing training programs at the University of Michigan and take advantage of substantial resources and a rich clinical research base to foster the careers of new investigators. Specific aims are to: 1) teach clinical investigators how to develop a research project with a testable hypothesis, appropriate methodology, and statistically sound study design and data analysis; 2) promote knowledge of ethical issues in clinical research; 3) develop grant writing and scientific communication skills; 4) develop more advanced skills necessary for specific types of translational research and clinical trials; 5) provide for "hands-on" clinical research under the guidance of an experienced mentor; and 6) increase the recruitment of scholars from underrepresented ethnic and racial groups into clinical research. The institution will make a major commitment to recruit underrepresented scholars by providing tuition and stipend assistance. Three major academic resources will provide the pillars of strength for the program: a) a nationally recognized instructional program in Clinical Research Design and Statistical Analysis; b) a superb NIH funded General Clinical Research Center (GCRC) and c) a newly established Center for Clinical Investigation and Therapeutics. Participating in the program are the Schools of Medicine, Dentistry, Public Health and Nursing and the College of Pharmacy. The focus of this training will be postdoctoral fellows in clinical departments, junior faculty, and mid-career healthcare professional who wish to re-establish credentials in clinical research. The two-year program will result in a Master of Science degree. The program will have five main components: 1) a didactic core curriculum; 2) complementary specialized tracks; 3) a 12 month mentored clinical research project; 4) monthly seminars and 5) yearly symposia with visiting faculty. These various activities will be carried out concurrently. While the core curriculum will provide general basic skills in clinical research design, the elective complementary tracks will help trainees develop skills required for specific areas of research. These tracks will focus on drug development and randomized clinical trials; outcomes research, and translational application of new technologies in clinical research. The success of the program will be measured by the graduates' ability to obtain extramural federal funding and national recognition for their research. Specifically, we will track career development for five years after graduation in terms of CAP and K23 awards, academic positions and progress, and their productive roles in clinical research and collaborations. The effectiveness of the major components of the program will be evaluated by an internal, independent process which will enable the Program director and the Advisory Committee to revise and refine the program curriculum.

密歇根大学临床研究培训项目将精简、升级和整合密歇根大学现有的培训项目，并利用大量资源和丰富的临床研究基础来培养新研究者的职业生涯。 具体目标是：1）教导临床研究人员如何开发具有可检验假设、适当方法论以及统计上合理的研究设计和数据分析的研究项目； 2）促进临床研究中伦理问题的了解； 3）培养资助写作和科学沟通技巧； 4) 培养特定类型转化研究和临床试验所需的更高级技能； 5）在经验丰富的导师指导下提供“实践”临床研究； 6) 增加招募来自代表性不足的民族和种族群体的学者参与临床研究。 该机构将做出重大承诺，通过提供学费和津贴援助来招募代表性不足的学者。 三个主要学术资源将为该计划提供力量支柱：a）国家认可的临床研究设计和统计分析教学计划； b) 一流的 NIH 资助的普通临床研究中心 (GCRC) 和 c) 新成立的临床研究和治疗中心。 参与该计划的有医学院、牙科学院、公共卫生学院和护理学院以及药学院。 此次培训的重点将是希望重新建立临床研究资格的临床部门的博士后研究员、初级教师和职业中期医疗保健专业人员。 这个为期两年的课程将获得理学硕士学位。 该计划将有五个主要组成部分：1）教学核心课程； 2）互补的专业赛道； 3）为期12个月的指导临床研究项目； 4) 每月研讨会和 5) 每年与客座教授举行的研讨会。 这些不同的活动将同时进行。 虽然核心课程将提供临床研究设计的一般基本技能，但选修的补充课程将帮助学员发展特定研究领域所需的技能。 这些轨道将侧重于药物开发和随机临床试验；结果研究以及新技术在临床研究中的转化应用。 该计划的成功将取决于毕业生获得校外联邦资助和国家对其研究的认可的能力。 具体来说，我们将跟踪毕业后五年的职业发展，包括 CAP 和 K23 奖项、学术职位和进展，以及他们在临床研究和合作中的富有成效的作用。 该计划主要组成部分的有效性将通过内部独立流程进行评估，该流程将使计划主任和咨询委员会能够修改和完善计划课程。

项目成果

Peripheral nerve vasculitis presenting as complex regional pain syndrome.

周围神经血管炎表现为复杂的局部疼痛综合征。

• DOI: 10.1097/cnd.0b013e31818d4e8b
• 发表时间: 2008
• 期刊: Journal of clinical neuromuscular disease
• 作者: Ramchandren,Sindhu;Chaudhry,Vinay;Hoke,Ahmet;Murinson,BethB;Cornblath,DavidR;Treisman,GlennJ;Griffin,JohnW
• 通讯作者: Griffin,JohnW

Headache in a patient with Klinefelter's syndrome and hyperostosis frontalis interna.

克兰费尔特综合征和额内骨质增生患者的头痛。

• DOI: 10.1007/s10194-007-0426-3
• 发表时间: 2007
• 期刊: The journal of headache and pain
• 作者: Ramchandren,Sindhu;Liebeskind,DavidS
• 通讯作者: Liebeskind,DavidS

Peripheral neuropathy in survivors of childhood acute lymphoblastic leukemia.

• DOI: 10.1111/j.1529-8027.2009.00230.x
• 发表时间: 2009-09
• 期刊: Journal of the peripheral nervous system : JPNS
• 作者: Ramchandren S;Leonard M;Mody RJ;Donohue JE;Moyer J;Hutchinson R;Gurney JG
• 通讯作者: Gurney JG